The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis

T Rosenow, LC Mok, L Turkovic… - European …, 2019 - Eur Respiratory Soc
Pulmonary inflammation and infection are important clinical … in cystic fibrosis (CF). However,
whether in young children they are transient findings or have cumulative, long-term impacts

[HTML][HTML] The cumulative effects of intravenous antibiotic treatments on hearing in patients with cystic fibrosis

AC Garinis, CP Cross, P Srikanth, K Carroll… - … of Cystic Fibrosis, 2017 - Elsevier
… for treating life-threatening respiratory infections in patients with cystic fibrosis (CF). The goal
of this study was to examine the effects of cumulative intravenous (IV)-AG (amikacin and/or …

Defining and identifying early‐onset lung disease in cystic fibrosis with cumulative clinical characteristics

L Huang, HCJ Lai, N Antos, MJ Rock… - Pediatric …, 2022 - Wiley Online Library
first year of life, cumulative over 1–2 years, and cumulative over 1–3 years using a novel
scoring system we developed and refer to as CFELD for CF early-… the Wisconsin Cystic Fibrosis

[HTML][HTML] Cystic fibrosis in young children: a review of disease manifestation, progression, and response to early treatment

DR VanDevanter, JS Kahle, AK O'Sullivan… - … of Cystic Fibrosis, 2016 - Elsevier
… illness associated with cystic fibrosis (CF) early in life, but … and cumulative damage begin to
occur in persons with CF. … consistent with early disease progression can be observed early in …

Impact of inhaled corticosteroids on the risk of early Pseudomonas aeruginosa acquisition in cystic fibrosis

L Minicucci, G Severi, L Cresta, A Giannattasio… - Acta …, 2003 - Wiley Online Library
… of Pseudomonas aeruginosa acquisition before the age of 10 y in cystic fibrosis (CF) patients.
Methods: For each subject the cumulative dose kg À1 of IC received for each year of age …

Determinants of lung disease progression measured by lung clearance index in children with cystic fibrosis

S Stanojevic, SD Davis, L Perrem… - European …, 2021 - Eur Respiratory Soc
… We would expect to observe a trend in the effects of cumulative hospitalisations; however,
only a few patients had multiple hospitalisations in this study population. A comprehensive …

Early childhood growth in patients with cystic fibrosis

PJ Byard - Annals of human biology, 1990 - Taylor & Francis
Early childhood growth in cystic fibrosis is characterized by … in the first year of life followed by
an earlier approach to a … the cumulative effect of chronic digestive or pulmonary malfunctions…

Effect of pulmonary exacerbations treated with oral antibiotics on clinical outcomes in cystic fibrosis

S Stanojevic, A McDonald, V Waters, S MacDonald… - Thorax, 2017 - thorax.bmj.com
… We then examined the cumulative effect of oPExs on lung function decline during the entire
study period. The overall rate of FEV 1 decline for the study population was −1.1% per year (…

Improved survival in cystic fibrosis patients diagnosed by newborn screening compared to a historical cohort from the same centre

FN Dijk, K McKay, F Barzi, KJ Gaskin… - Archives of disease in …, 2011 - adc.bmj.com
… before the impact of a worse clinical state is actually demonstrable on survival might be due
to a cumulative effect of non-recoverable pulmonary and nutritional compromise from early

Radiologic imaging in cystic fibrosis: cumulative effective dose and changing trends over 2 decades

OJ O'Connell, S McWilliams, AM McGarrigle… - Chest, 2012 - Elsevier
… with cystic fibrosis (CF), and a known predisposition to certain cancers, cumulative radiation
… This study explores the estimated cumulative effective radiation dose over a 17-year period …