… CRS can be induced by direct target cell lysis with consecutive release of cytokines like … to
therapeutic stimuli with subsequent cytokine release. These cytokines trigger a chain reaction …

… Cytokine release syndrome (CRS) … cytokines including interleukin (IL)-6 and interferon
γ, and uncontrolled studies demonstrate that immunosuppression using tocilizumab, an anti-IL-6 …

… Use of CART cells has brought a unique set of toxicities such as cytokine release syndrome
(CRS) and neurotoxicity. Here, we provide an extensive overview of CRS, including risk …

… , leading to acute respiratory distress syndrome (ARDS), has been described in up to 20%
of COVID-19 cases. This is reminiscent of cytokine release syndrome (CRS)–induced ARDS …

… cytokine release syndrome (CRS) and neurologic toxicity. While the clinical manifestations
and risk factors for CRS with the two agents are similar, management strategies have critical …

… Cytokine release syndrome (CRS) and neurotoxicities (CAR-related encephalopathy syndrome…
mediating CRS and CRES by releasing IL-1 and IL-6 among other cytokines. Blocking IL-…

… We and others have observed a cytokine release syndrome (… effector cytokines, such as
interferon-γ, cytokines associated … activation syndrome, such as interleukin (IL)-10 and IL-6, may …

… Proposed pathophysiology for the development of severe cytokine release syndrome …
amounts of IL-6, IL-1, and other cytokines and chemokines. Activated endothelium releases stored …

… syndrome is a kind of toxic condition caused by the pro-inflammatory cytokines released …
In fact, up to some extent, the cytokine release may be an indicator of the antitumor effects of …

… An important toxicity seen with a few mAbs is cytokine-release syndrome (CRS). These …
with CRS, the cytokines involved and putative mechanisms mediating cytokine release will be …