Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
… Also, we searched in ClinicalTrials for ‘COVID-19’ ongoing studies … cytokine storm. From
this, we also researched the same databases for the rationale of using those drugs in COVID-19

Th1/Th2/Th17 cytokine profile among different stages of COVID-19 infection

G Gupta, I Shareef, S Tomar, MSN Kumar… - National Academy …, 2022 - Springer
… This study suggests increase of pro-inflammatory cytokines in COVID-19 patients and may
be helpful in development of predictive models to predict severe disease at early stages SARS…

Age-severity matched cytokine profiling reveals specific signatures in Covid-19 patients

R Angioni, R Sanchez-Rodriguez, F Munari… - Cell death & …, 2020 - nature.com
… In addition to the deregulated cytokine response, COVID-19 … , and defective lymphocyte
responses were reported in … immune responses and unsolved inflammation in COVID-19 patients…

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… status in patients with COVID-19, could be helpful for … , at least at present, in COVID-19.
Currently available experimental and … COVID-19, with a specific focus on their role in the cytokine

[HTML][HTML] Hazards of the cytokine storm and cytokine-targeted therapy in patients with COVID-19

M Quirch, J Lee, S Rehman - Journal of medical Internet research, 2020 - jmir.org
… during the early stages of the COVID-19 pandemic, ranging from targeting the virus … cytokine
response. Among the different agents to manage cytokine storm in patients with COVID-19, …

Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll‐like receptors dictates pathophysiology of COVID19 disease

MK Vakil, Y Mansoori, GRL Al‐Awsi… - Journal of Medical …, 2022 - Wiley Online Library
… Therefore, in this study, those genetic variations mostly of encoding genes associated with
the immune responses to the COVID-19 disease predisposition or individual vulnerability …

Immune response in COVID-19: what is next?

Q Li, Y Wang, Q Sun, J Knopf, M Herrmann… - Cell Death & …, 2022 - nature.com
… of pro-inflammatory cytokines was early identified in severe COVID-19 patients [66]. The
detection of viral RNA potentially drives activation of this transcriptional response by endosomal …

Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
… -CSS has led to the off-label use of targeted anti-cytokine therapies aimed at blocking …
cytokine blockade in COVID-19. Currently there are no standard therapies for COVID-19 or COVID-…

Serum cytokine levels of COVID-19 patients after 7 days of treatment with Favipiravir or Kaletra

E Mortaz, A Bassir, ND Roofchayee, NK Dezfuli… - International …, 2021 - Elsevier
… In contrast, serum levels of IL-6, IL-8 and IFNγ were elevated at baseline in COVID-19
subjects compared to healthy subjects with IL-6 (p = 0.006) and IL-8 (p = 0.011) levels being …

Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm

PA Mudd, JC Crawford, JS Turner, A Souquette… - Science …, 2020 - science.org
… exhibiting the T H 22 signature are plotted separately for visual comparison, they were
considered to represent regulated cytokine responses and were therefore included as COVID-…