The advent of the cytokine storm

IA Clark - Immunology and cell biology, 2007 - search.proquest.com
… In fact it began in infectious disease in 1981, malaria in particular, although it has … bacterial
infections and its iatrogenic twin, the Jarisch–Herxheimer syndrome. Although cytokine storm

[HTML][HTML] Cytokine storms in infectious diseases

JR Teijaro - Seminars in immunopathology, 2017 - Springer
… The term “cytokine storm” has been adopted in the past several decades as a phrase to …
following severe viral and bacterial infections. However, “cytokine storm” was initially coined in …

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… Antibiotics are the best known and most widely used weapon to combat bacterial infections.
When antibiotics were discovered in the first half of the 20th century (29), they were heralded …

[HTML][HTML] Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
… Additionally, the expression of specific TLRs is usually upregulated in response to severe
bacterial infections and this could further aggravate the pro-inflammatory immune response …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
cytokine storm induced by COVID-19. In addition, we suggest that the identification and
treatment of the cytokine storm … IL-1 receptor antagonists increase the risk of bacterial infections, …

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
bacterial infections), and generate pain, thereby warning the host of the local responses.
These responses often occur at the expense of local organ function, particularly when tissue …

[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been described as a collection of clinical …
Cytokine storms (CSs) are associated with various pathologies, as observed in infectious

[HTML][HTML] Agents to reduce cytokine storm

H Gerlach - F1000Research, 2016 - ncbi.nlm.nih.gov
… for cytokine storm in infections 6 . Several hundred articles have since followed, and other
clinical syndromes were brought into the context of cytokine storm … against bacterial toxins or …

[HTML][HTML] Critical roles of cytokine storm and bacterial infection in patients with COVID-19: Therapeutic potential of mesenchymal stem cells

B Arjmand, S Alavi-Moghadam, M Sarvari… - …, 2023 - Springer
… pivotal role in the recovery of infectious diseases such as COVID-… cytokines, known as
a "cytokine storm," can deteriorate the patient's clinical condition. Secondary bacterial co-infection

[HTML][HTML] Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… also in bacterial infections in terms of enhancing anti-bacterial host responses [171,172].
Thus, IFNs are an attractive virulence target for bacterial pathogens. Bacteria secrete effectors …