… In fact it began in infectious disease in 1981, malaria in particular, … cytokine storm can be
a useful lay term, we must expect clinical and pathological dissimilarities in systemic diseases …

… cellular and molecular mechanisms contributing to the cytokine storm in viral disease (66,
81), … absent or aberrantly regulated, then the outcome may contribute toward a cytokine storm. …

… At the end of 2019, the disease caused by severe acute respiratory syndrome coronavirus
2 … cytokines in patients with COVID‐19, suggesting the existence of cytokine storm in some …

… as a cytokine storm in cases of severe COVID-19. A cytokine storm is a potentially fatal immune
disease … of COVID-19 outcome. Interestingly, Ong et al 45 revealed that the levels of most …

… These cytokines are elevated in most patients with CSS, as … Various infectious and
noninfectious diseases have a causal … disease characterized by uncontrolled cytokine storm. HLH …

… Why has the “cytokine storm” been so closely associated with COVID-19? During the SARS
… , the term cytokine storm was described as a feature and associated with adverse outcomes. …

… with better outcomes. In the study, elevated CRP levels and IL-6 levels were linked to disease
… In this study, the outcomes of twelve patients who received baricitinib along with standard …

… nonuniformity in outcome assessment and varied definitions of disease severity… cytokine
storm were therefore considered to be the most critical contributors to adverse clinical outcomes …

… Overall, the discovery of the link between the IFNλ3 locus and HCV disease outcome has
been a huge step forward for the field. However, while it has provided momentum for clinicians …

… For these diseases, it has been proposed that downregulating inflammatory immune … improve
outcome. We review some of the current candidates for treatment of cytokine storms which …