When does the cytokine storm begin in COVID-19 patients? A quick score to recognize it

S Cappanera, M Palumbo, SH Kwan, G Priante… - Journal of clinical …, 2021 - mdpi.com
… After reviewing published studies, we proposed a Cytokine Storm Score (CSs) to identify …
and poorer outcomes. We retrospectively analyzed 31 patients admitted to Infectious Disease

Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
… cardiovascular disease are at increased risk of cytokine storm (4, 18) and poor outcomes. …
COVID-19 induced cytokine storm may be contributing to the poor outcomes in elderly patients …

Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
… However, more research is needed to improve treatment outcomes, Such … cytokine storms
caused by various diseases [1]. In conclusion, cytokine storms caused by infectious diseases

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… course of the disease, will be taken … cytokine storm and how their concentrations may reflect
the degree of severity of COVID-19 as well as how their changes parallel the clinical outcome

The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
… the outcome of disease. Although the precise molecular events surrounding cytokine storm
… used in combination to obtain a better outcome. Based on the promising results mentioned …

On the alert for cytokine storm: immunopathology in COVID‐19

LA Henderson, SW Canna, GS Schulert… - Arthritis & …, 2020 - Wiley Online Library
… Poor outcomes in COVID-19 correlate with clinical and laboratory features of cytokine storm
… hyperinflammation and multiorgan disease arise through excessive cytokine release from …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… The term ‘cytokine storm syndrome’ is perhaps one of the critical hallmarks of COVID-19
disease … the incidence of COVID-19 induced AKI and thus improves outcomes and survival. …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
… risk for severe disease outcomes (ie, elderly, select preexisting conditions). Although we
know there is a link between disease severity, viral production, and a cytokine storm or cytokine

Lipotoxicity and cytokine storm in severe acute pancreatitis and COVID-19

P Hegyi, Z Szakács, M Sahin-Tóth - Gastroenterology, 2020 - gastrojournal.org
… -19 to severe, potentially fatal disease. Early supplementation with calcium and albumin to
cytokine storm by extracorporeal cytokine adsorption may prevent dismal disease outcomes

COVID-19: in the eye of the cytokine storm

R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
… as sepsis and the cytokine storm responsible for the poor outcomes in SARS and MERS
show a strong time dependence between cytokine levels and disease progression. We propose …