The multifaceted immunology of cytokine storm syndrome

PY Lee, RQ Cron - The Journal of Immunology, 2023 - journals.aai.org
Cytokine storm syndromes (CSSs) are potentially fatal hyperinflammatory states that share
the underpinnings of persistent immune cell activation and uninhibited cytokinecytokines. …

Tackling the cytokine storm using advanced drug delivery in allergic airway disease

VK Patel, S Vishwas, R Kumar, G De Rubis… - Journal of Drug Delivery …, 2023 - Elsevier
… , chemotherapeutic agents, and immunotherapeutic agents to treat various diseases [43]. …
could be a promising alternative to current treatment options such as β 2 agonists and ICS. …

[HTML][HTML] Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

G Suntharalingam, MR Perry, S Ward… - … England Journal of …, 2006 - Mass Medical Soc
… Lymphopenia has been observed as part of the cytokine storm … T-cell agonist drug rather
than to the cytokine storm alone. … and 6), and consisted of the cytokine storm, involving the rapid …

Cytokine storm and signaling pathways: pathogenesis of SARS‐CoV‐2 infection, managing and treatment strategies

R Kumar, K Gulia - 2021 - wlv.openrepository.com
… , an immunotherapeutic strategy will be effective for the suppression of cytokine storms and
… The option to counter the progression of cytokine storm can only be possible if a proper …

In the eye of the storm: immune-mediated toxicities associated with CAR-T cell therapy

JG Borrega, P Gödel, MA Rüger, ÖA Onur… - …, 2019 - journals.lww.com
… , treatment options remain limited … cytokines lead to an activation of bystander immune cells
and endothelial cells which in turn activate more immune cells culminating in a cytokine storm

Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
… distress syndrome is the so-called “cytokine storm,” which is an aberrant response from the
cytokines/chemokines. In this review, we will discuss the role of cytokine storm in COVID-19 …

Immunomodulatory therapy for the management of severe COVID-19. Beyond the anti-viral therapy: A comprehensive review

J Alijotas-Reig, E Esteve-Valverde, C Belizna… - Autoimmunity …, 2020 - Elsevier
… , the so-called “cytokine storm”. The reduction of this … therapy could be a therapeutic option.
However, right data on the … ], we think the IVIG option should be carefully analyzed before its …

The possible of immunotherapy for COVID-19: A systematic review

A AminJafari, S Ghasemi - International immunopharmacology, 2020 - Elsevier
cytokines, specificity of IL-6 in COVID-19 comes from that Elevated IL-6 is correlated with
inflammatory cytokine storm … , immunotherapy is an efficient therapeutic option intervention …

A guide to immunotherapy for COVID-19

FL van de Veerdonk, E Giamarellos-Bourboulis… - Nature medicine, 2022 - nature.com
… Therefore, we aim to provide guidance on immunotherapeutic … guidance with possible
treatment options for when patients … still an option to start corticosteroids and anti-IL-6 treatment. …

Role of PKM2-mediated immunometabolic reprogramming on development of cytokine storm

Z Liu, Y Le, H Chen, J Zhu, D Lu - Frontiers in immunology, 2021 - frontiersin.org
… is the leading cause of death in many inflammatory diseases, effective therapy options for
treating cytokine storm storms have not been fully explored. A previous study reported that …