Immunotherapies and immunomodulatory approaches in clinical trials-a mini review

M Iqbal Yatoo, Z Hamid, I Rather… - … immunotherapeutics, 2021 - Taylor & Francis
… 14 cytokine therapies Citation15,Citation16 and immune modulators are some of the
immunotherapeutic options … inflammatory cascade by modulating cytokine storm when most of the …

[PDF][PDF] Prospective approach to manage COVID-19-related cytokine storm; an updated review on current concepts

M Bahmani, L Saberian - Journal of Preventive Epidemiology, 2021 - researchgate.net
cytokine storm with immunomodulatory medications is one of the potential treatment options,
… Intravenous immunoglobulin immunotherapy for coronavirus disease-19 (COVID-19). Clin …

Immunobiology and immunotherapy of COVID‐19: A clinically updated overview

A Esmaeilzadeh, R Elahi - Journal of cellular physiology, 2021 - Wiley Online Library
cytokines could reduce the severity of the cytokine storm. Interventions that lead the immune
response through Th2-mediated immune responses are also among other options. These …

Continuous intravenous anakinra infusion to calm the cytokine storm in macrophage activation syndrome

LA Monteagudo, A Boothby… - ACR open rheumatology, 2020 - Wiley Online Library
… Clinicians often find, however, that these therapeutic options are not adequate, and … of
biologics and immunotherapies, case reports have described other therapeutic options for MAS, …

Of bats and men: Immunomodulatory treatment options for COVID-19 guided by the immunopathology of SARS-CoV-2 infection

MJ Christie, AT Irving, SC Forster, BJ Marsland… - Science …, 2021 - science.org
… on selecting the most appropriate immunotherapeutic agents and timing their administration…
those running rampant during COVID-19 and its cytokine storm. Hence, kinase inhibitors [eg, …

Fine tuning the cytokine storm by IFN and IL-10 following neurotropic coronavirus encephalomyelitis

C Savarin, CC Bergmann - Frontiers in immunology, 2018 - frontiersin.org
… Confirmation of similar pathways in multiple viral encephalomyelitis models will ultimately
enhance targeted treatment options at early stages of disease manifestation. Accumulating …

Risk factors associated with the clinical outcomes of COVID-19 and its variants in the context of cytokine storm and therapeutics/vaccine development challenges

J Hanna, P Tipparaju, T Mulherkar, E Lin, V Mischley… - Vaccines, 2021 - mdpi.com
… Passive immunotherapy is a potential therapeutic option for treating MERS-CoV infections
as an alternative to currently marketed drugs such as remdesivir. The National Institute of …

Cytokine storm in COVID-19 and other diseases: emerging therapeutic interventions

S Sahu, R Dharra, M Gun, S Datta, AK Akela, A Kumar - Stem Cells, 2024 - Elsevier
… The coordinated production of cytokines occurs frequently during … of proinflammatory cytokines,
often termed as cytokine storm (CS)… Therapeutic options to treat cytokine storm in various …

[HTML][HTML] Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies?

C Constantinescu, S Pasca, T Tat… - … for ImmunoTherapy …, 2020 - ncbi.nlm.nih.gov
… response syndrome following massive cytokine release into the … Thus, five of them possibly
having an option of subsequent … review, might be a therapeutic option for refractory CRS.8 …

Cytokine storm”, not only in COVID-19 patients. Mini-review

N Lukan - Immunology Letters, 2020 - Elsevier
… Additional research is clearly needed to fully understand the mechanisms of intensive rise
of cytokine storm and search for appropriate treatment options. Some preclinical studies are …