Cytokine storm in a mouse model of IgG-mediated hemolytic transfusion reactions

EA Hod, CM Cadwell, JS Liepkalns… - Blood, The Journal …, 2008 - ashpublications.org
… Thus, in our murine HTR models, passive immunization with … (KO) mice, but only moderately
inhibited in C3 KO mice, … model to test the hypothesis that HTRs lead to cytokine storm

Nasal delivery of hesperidin/chitosan nanoparticles suppresses cytokine storm syndrome in a mouse model of acute lung injury

H Jin, Z Zhao, Q Lan, H Zhou, Z Mai, Y Wang… - Frontiers in …, 2021 - frontiersin.org
… The cytokine storm or cytokine storm syndrome (… mouse model of inflammatory lung disease,
the HPD/NPs markedly inhibited lung injury as evidenced by reduced inflammatory cytokine

[HTML][HTML] The ACE2‐deficient mouse: A model for a cytokine storm‐driven inflammation

J Wang, N Kaplan, J Wysocki, W Yang, K Lu… - The FASEB …, 2020 - ncbi.nlm.nih.gov
… , 17 A cytokine storm is a consequence of the secretion of a large number of cytokines and
… , 19 Cytokine storms are known to occur in autoimmune diseases 20 and can be triggered by …

SOCS4 expressed by recombinant HSV protects against cytokine storm in a mouse model

S Ren, X Chen, R Huang, GG Zhou… - Oncology …, 2019 - spandidos-publications.com
… that the concept of cytokine storm was much more … cytokine storm remains limited, and
countermeasures to control the balance between appropriate cytokine release and cytokine

The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
… Neutralization of tumor necrosis factor (TNF) and interferon (IFN)-γ can prevent cell death
and inhibit the occurrence of a CS in mouse models of severe acute respiratory syndrome-…

A mathematical model of cytokine dynamics during a cytokine storm

M Waito, SR Walsh, A Rasiuk, BW Bridle… - … Approaches in Advancing …, 2016 - Springer
… Following administration of a highly attenuated virus to mice with leukocytes lacking the
type I IFN receptor, a deadly cytokine storm developed leading to death in only 24 h. Down-…

Small molecule inhibitor CRT0066101 inhibits cytokine storm syndrome in a mouse model of lung injury

B Cui, Y Liu, J Chen, H Chen, Y Feng… - International …, 2023 - Elsevier
… To investigate whether the PKD inhibitor CRT0066101 could function in LPS-induced
cytokine storms, we used LPS to establish a mouse model of acute lung injury. The mice were …

Anti‑inflammatory effect of metformin against an experimental model of LPS‑induced cytokine storm

I Taher, E El‑Masry… - Experimental and …, 2023 - spandidos-publications.com
… the impact of metformin in the mouse model used in the present study. In the present study,
a mouse model of LPS-induced cytokine storm was pretreated with metformin, which was …

Transmembrane TNF-α as a Novel Biomarker for the Diagnosis of Cytokine Storms in a Mouse Model of Multiple Organ Failure

P Yang, Y Zeng, F Yang, X Peng, Y Hu, X Tan, R Zhang - Inflammation, 2023 - Springer
… A cytokine storm (CS) is … mouse model in this study showed that the tmTNF-α expression
changes in the neutrophils differed from the serum TNF-α and serum IL-18, INF-γ, IL-4, and IL-6. …

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
… of a cytokine storm and the biological consequences of cytokine overproduction. We will also
look at the cytokine storm … A combination of knockout mouse models and pharmacological …