Machine-learning-assisted microfluidic nanoplasmonic digital immunoassay for cytokine storm profiling in COVID-19 patients

Z Gao, Y Song, TY Hsiao, J He, C Wang, J Shen… - ACS …, 2021 - ACS Publications
cytokines across a wide dynamic range at high-throughput. In this study, we report a
machine-learning-… to meet the rising demand for cytokine storm monitoring in COVID-19 patients. …

[HTML][HTML] Meta-analysis informed machine learning: Supporting cytokine storm detection during CAR-T cell Therapy

A Bogatu, M Wysocka, O Wysocki, H Butterworth… - Journal of Biomedical …, 2023 - Elsevier
… analysis of specific cytokine and chemokine … machine learning algorithms and set out to
pioneer a meta-review informed method for the identification of CRS based on specific cytokine

A machine learning based modeling of the cytokine storm as it relates to COVID-19 using a virtual clinical semantic network (vCSN)

A Rahman, J Kriak, R Meyer… - … conference on big …, 2020 - ieeexplore.ieee.org
… This paper presents a machine learning based modeling … understanding the phenomenon
of cytokine storm as it relates … severest patients experiencing the cytokine storm. Currently we …

[PDF][PDF] Calming the Storm: Identifying Multi-Cytokine Inhibiting Drugs with Machine Learning for COVID-19 Induced Cytokine Storms

J Hou, VL Kouznetsova, IF Tsigelny - Microbiol Infect Dis, 2022 - scivisionpub.com
… : the cytokine storm. The cytokine storm is composed of many cytokines, including IL-6, IL-2, …
To combat such effects, a cocktail of cytokine-inhibiting drugs are administered. However, a …

[HTML][HTML] DeepNEU: a machine learning platform for simulating Cytokine Storm and Coagulopathy that complicate severe COVID-19 to enable targeted drug …

S Esmail, WR Danter - 2021 - europepmc.org
… treating both the cytokine storm and coagulopathy associated with … the cytokine storm and
coagulopathy that often complicate severe COVID-19, (3) the unsupervised machine learning

Machine learning identifies ponatinib as a potent inhibitor of SARS-CoV2-induced cytokine storm

M Chan, S Vijay, MJ McElrath, EC Holland, TS Gujral - bioRxiv, 2021 - biorxiv.org
… of the cytokine storm is … trigger cytokine storm in monocytes, and we identify and validate
FDA-approved or clinical grade compounds that inhibit the production of inflammatory cytokines

Machine learning identifies molecular regulators and therapeutics for targeting SARS‐CoV2‐induced cytokine release

M Chan, S Vijay, J McNevin, MJ McElrath… - Molecular systems …, 2021 - embopress.org
… phenotypic screening with machine learning-based modeling, … of NTD-induced cytokine
production, implicating the role of … Drugs or drug combinations that reduce the cytokine storm, …

[HTML][HTML] Repurposing of drugs for combined treatment of COVID-19 cytokine storm using machine learning

MR Gantla, IF Tsigelny, VL Kouznetsova - Medicine in Drug Discovery, 2023 - Elsevier
cytokine storm-related pathway. These may be useful drugs to treat patients because these
therapies can fight cytokine storm … We used machine learning to expedite the drug discovery …

Machine learning-based cytokine microarray digital immunoassay analysis

Y Song, J Zhao, T Cai, A Stephens, SH Su… - Biosensors and …, 2021 - Elsevier
… immunoassay by incorporating machine learning-based … analysis algorithm based on machine
learning with a convolutional … ill COVID-19 patients developing cytokine storm syndrome. …

Can tocilizumab calm the cytokine storm of COVID-19?

GS Schulert - The Lancet Rheumatology, 2020 - thelancet.com
… , machine-learning … of machine learning for analysis of large, complex datasets, in The
Lancet Rheumatology, George Robinson and colleagues1 successfully applied machinelearning