5 天前 - … mechanisms could contribute to SARS-CoV-2-associated-lymphopenia. The
fundamental mechanism is the inflammatory cytokine storm … the molecular mechanisms underlying …

26 天前 - … The hallmark of COVID-19 pathogenesis is the cytokine storm with elevated levels
of IL-1, IL-6, TNF-α, and GM-CSF [4]; all of these cytokines are produced by human MCs, as …

35 天前 - … its role in the development of cytokine storm during severe HFMD. In this … the
molecular mechanism of severe HFMD through examining macrophage-associated cytokine storm …

35 天前 - … Vasculopathy generally, and endothelial dysfunction, hypercoagulability, and
microthrombi in particular, can be induced by cytokine storms following infection and is a common …

38 天前 - … of inflammatory cytokines, the induction of hypoxia, and the triggering of cytokine
storms. … These findings suggest further research into the molecular mechanisms involved in …

38 天前 - … Top biological pathways were pathogen induced cytokine storm signalling (P FDR
=3.2x10 … TNF, a cytokine master regulator of inflammatory signaling, was identified as the top …

41 天前 - … -viral response, and secretion of cytokines and chemokines. STC-15, a first in class
small molecule inhibitor of METTL3 developed by Storm Therapeutics, demonstrated in pre-…

43 天前 - … These phospholipids also induce osteoblasts to secrete cell cytokines such as IL‑6
and TNF‑α, both of which contribute to osteoclast differ‑ entiation (96). Neutralization of …

43 天前 - … Furthermore, it can exacerbate tissue damage and contribute to the cytokine
storm. Understanding the mechanisms and consequences of SARS-CoV-2 Spike Protein 1-…

47 天前 - … mechanisms by which SARS-CoV-2 induces AVDS and subsequently MIS. Key
materials include molecular … severe endothelial dysfunction, cytokine storms, and mitochondrial …