… mechanism remains unclear, lower levels of type-1 interferon have been associated with increased MAS and worsening cytokinestorm … pro-inflammatory cytokines have been reported […
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… levels of pro-inflammatory cytokines are produced during the crosstalk between epithelial cells and immune cells in COVID-19, which has linked the cytokinestorm (CS) with the severe …
… about the real molecularmechanism of activity of tocilizumab. … IL-6) and can inhibit both classical and trans signaling pathway (Figure 1). Though the underlying molecularmechanism of …
Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
… To lower mortality due to cytokinestorm, we summarized the clinical and … cytokinestorm. We explored the efficacy and safety of potential treatments and their molecularmechanism. …
… This virus induces an intense cytokine response called cytokinestorm in a group of patients with severe/critical form. This event, in turn, results in serious clinical outcomes such as …
A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… prominent cytokine … cytokine levels while discussing cytokine sources and biological functions. Finally, we discuss in brief potential therapies attempting to modulate the cytokinestorm. …
… and molecularmechanisms contributing to the cytokinestorm in … Thus, it would be worth to focus on the cytokinestorm in the … methods are revealing new insights into the cytokinestorm. …
C Datta, A Bhattacharjee - Journal of …, 2020 - immunologyresearchjournal.com
… to describe how cytokinestorm is associated … cytokinestorm during COVID-19 infection using several interleukin receptor antagonists, inhibitors, intravenous immunoglobulins, cytokine …
F Ahmed - Frontiers in immunology, 2020 - frontiersin.org
… D supplementation reduces the risk of the cytokinestorm. However, the underlying molecular mechanism of Vitamin D in suppressing the cytokinestorm and reducing viral infection in …