Autoinflammatory diseases and cytokine storms—imbalances of innate and adaptative immunity

A Marcuzzi, E Melloni, G Zauli, A Romani… - … Journal of Molecular …, 2021 - mdpi.com
cytokines in response to various triggering stimuli. Moreover, hyperinflammation is of great
interest, as it is one of the main manifestations of COVID-19 infection, and the cytokine storm

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
… Current knowledge of cytokine and chemokine secretions resulting from host immunological
responses to SARS-CoV-2 infection, cytokine storm (CS), and related therapeutic …

[HTML][HTML] Molecular mechanisms of organ damage in sepsis: an overview

G Sygitowicz, D Sitkiewicz - Brazilian Journal of Infectious Diseases, 2021 - SciELO Brasil
… An uncontrolled inflammatory response, often referred to as "cytokine storm", leads to an
increase in oxidative stress as a result of the inhibition of cellular antioxidant systems. Oxidative …

The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
… of the mechanism that promotes a cytokine storm remains limited. In this review, we focus
on the potential mechanisms responsible for severe influenza-induced cytokine storm and the …

The mechanism of superantigen-mediated toxic shock: not a simple Th1 cytokine storm

L Faulkner, A Cooper, C Fantino… - The Journal of …, 2005 - journals.aai.org
… a systemic release of proinflammatory cytokines, including IL-… our understanding of the
mechanisms involved in toxic shock… is the cumulative Th1 cytokine storm elicited by excessive T …

[HTML][HTML] Natural products for treating cytokine storm–related diseases: Therapeutic effects and mechanisms

M Liu, Q Wang, W Xu, J Wu, X Xu, H Yang… - Biomedicine & …, 2023 - Elsevier
Cytokine storm (CS) is primarily observed in cases of sepsis and infectious … and cytokines
involved in CS-related diseases are depicted in Fig. 1. Cytokines are a group of low-molecular-…

Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets

V Kumar - International immunopharmacology, 2020 - Elsevier
… implicated in these negative feedback mechanisms. These molecules and mechanisms can
be targeted for developing novel therapeutic drugs for cytokine storm-associated diseases, …

[PDF][PDF] A potential mechanism for triggering cytokine storm in Covid-19 patients

H Butterweck, A Weber - COJ Biomed Sci Res, 2020 - milandmc.com
… Abstract Infection with SARS-CoV-2 can result in severe disease characterized by cytokine
storm and systemic inflammation. Despite huge efforts, there is only initial evidence that the …

Pathogenesis and treatment of cytokine storm in COVID-19

M Soy, G Keser, MP Atagündüz - Turkish Journal of Biology, 2021 - journals.tubitak.gov.tr
… A hyperinflammatory state resulting in a cytokine storm and adult respiratory distress …
mechanisms have been suggested in the pathogenesis of COVID-19 associated cytokine storm (…

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
… for the cytokine storm in … cytokine storm in severe COVID-19. We believe that TPE is able
to effectively remove inflammatory cytokines from the blood and can improve cytokine storm 7 . …