What Is Cytokine Storm?

D Jarczak, A Nierhaus - … of Dysregulated Immune Response in the …, 2023 - Springer
… , are referred to as “cytokine storm” and can lead to serious … and thus trigger a cytokine
storm. Certain pathogens or … immunological disbalance with formation of a cytokine storm. …

Targeting purinergic receptors to suppress the cytokine storm induced by SARS-CoV-2 infection in pulmonary tissue

JLB Simões, HF Basso, GC Kosvoski, J Gavioli… - International …, 2021 - Elsevier
… trigger the so-called “cytokine storm”. This process generates … of COVID-19 is a cytokine
storm, one of which is responsible for … The cytokine storm mechanism during a viral infection is …

[HTML][HTML] Targeting Specific Checkpoints in the Management of SARS-CoV-2 Induced Cytokine Storm

A Rabiu Abubakar, R Ahmad, AB Rowaiye, S Rahman… - Life, 2022 - mdpi.com
cytokines known as cytokine storm syndrome. This article reported the various checkpoints
targeted to manage the SARS-CoV-2-induced cytokine storm. The … and cytokine storm were …

[HTML][HTML] Cytokine storm in COVID-19 and the treatment simulacrum

A Karimi, SMR Hashemian - Biomedical and Biotechnology …, 2020 - journals.lww.com
mechanism of this ARDS in COVID-19 pneumonia is not known completely. There are ongoing
studies, but the term “cytokine storm” … molecular and cellular pathways of cytokine storms

[HTML][HTML] Cytokine storm signature in patients with moderate and severe COVID-19

O Kalinina, A Golovkin, E Zaikova, A Aquino… - … Journal of Molecular …, 2022 - mdpi.com
cytokine storm signatures in patients with acute COVID-19 and to investigate their influence
on severity of the infection. Plasma levels of 47 cytokines … pro-inflammatory cytokines (IL-6, IL-…

Comparing the cytokine storms of COVID-19 and pandemic influenza

LM Pacheco-Hernández… - … interferon & cytokine …, 2022 - liebertpub.com
cytokine storm syndromes (CSS) observed during COVID-19 and influenza to detect conserved
immunopathogenic mechanisms … research on specific cytokine networks implicated in …

[HTML][HTML] Inflammation triggered by SARS-CoV-2 and ACE2 augment drives multiple organ failure of severe COVID-19: molecular mechanisms and implications

M Iwasaki, J Saito, H Zhao, A Sakamoto, K Hirota, D Ma - Inflammation, 2021 - Springer
cytokine storm.” It has been indicated that early interventions to attenuate this cytokine storm
… -organ injuries and failure and the underlying mechanisms of COVID-19 that are associated …

[PDF][PDF] Cytokine storm syndrome in COVID-19: diagnosis and management strategies

S Maggo, P Dhull, AP Dubey, D Brashier… - Int J Health Sci …, 2020 - researchgate.net
… to severe is immune dysfunction and cytokine dysregulation resulting in what is called as
cytokine storm syndrome”. It is prudent to diagnose cytokine storm early in the course of …

CD8+ T Cell Biology in Cytokine Storm Syndromes

T Sekine, D Galgano, GP Casoni, M Meeths… - Cytokine Storm …, 2019 - Springer
… We also discuss how CD8 + T cells may promote or drive pathology in other cytokine release
syndromes (CSS). Moreover, we review the molecular mechanisms underpinning CD8 + T …

[HTML][HTML] Therapeutic role of tocilizumab in SARS-CoV-2-induced cytokine storm: rationale and current evidence

C Pelaia, C Calabrese, E Garofalo, A Bruni… - … Journal of Molecular …, 2021 - mdpi.com
… In this regard, the IL-6 receptor antagonist tocilizumab, a humanized monoclonal antibody
… of the cytokine storm caused by SARS-CoV-2 infection, as well as to focus on the molecular