… We performed an anatomical and pathological study in two patients died from COVID-19
and … macrophages that could result in “cytokine storm” or cytokine release syndrome (CRS). …

… of the cytokine storm; to describe the type, effects, and kinetics of cytokine production; and to
… For instance, patients with levels of pro-inflammatory cytokines are more likely to respond to …

… and curtail the cytokine storm in coronavirus 2019 (COVID-19) patients have become a … on
leukocyte and cytokine data associated with COVID-19 disease in 3939 patients in China and …

… increase of inflammatory cytokines in patients with COVID-19, suggesting the existence of
cytokine storm in some critical illness patients. Here, we summarize the pathogenesis, clinical …

… cell death that facilitates further pathogenic cytokine release, culminating in a … pathogenesis
of a CS and programmed cell death (PCD) processes. For example, during CSS in patients …

… to treating patients with cytokine storm syndromes. As … Using this paradigm of cytokine
storm pathogenesis, we … mechanisms of disease pathogenesis for therapeutic benefit. …

… patients. Many therapeutic strategies focusing on immunomodulation have been tested out
to assuage the cytokine storm in patients … response or cytokine storm with organ damage and …

… Additionally, an elevated serum IL–6 was observed in the … to the pathogenesis of “cytokine
storm syndrome” in patients with … The blockage of cytokine storm using anti-IL–6 or IL–6R …

… and thereby could aggravate cytokine storm (102). In the PBMCs of COVID-19 patients,
NF-κB … Induction of STREBP2 was found to enhance cytokine storm and the upregulation of …

… Sars-CoV pathogenesis shows a high … of cytokines [6]. Hyperactivation of pro-inflammatory
patterns, mainly characterized by cytokine storm, may increase risk of restenosis in patients …