… 2019 (COVID-19) pathogenesis is played by immune … of proinflammatory cytokines, known
as “a cytokine storm” (CS), … development in COVID-19 patients and integrate them into a …

… to emphasize some anti-cytokine drug and treatment modalities for COVID-19 patients.
Key words: … There is no clear evidence on the role of IL-6 in the pathogenesis of SARS-CoV-2. …

… Though no direct evidence can demonstrate that pro-inflammatory cytokines involve in
pathogenesis of coronavirus, some patients with severe disease provide the correlative facts that …

… CSF) and IL-6 have been selected to be analysed through intracellular cytokine staining, for
… as the primary cause of inflammatory cytokine storms in patients infected with SARS-CoV or …

… The actual composition of the cytokine storm at any point in time will show patient-to-patient …
We believe that it is premature at this early stage to discount CSS in the pathogenesis of …

… In this study, an IFN-γ-related cytokine and chemokine storm was found to be indeed present
in SARS patient and its … Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric …

… and pathogenesis of MERS-CoV and the development of therapeutics 3 . … as “cytokine
storm” 9 . High blood levels of cytokines and chemokines have been detected in patients with …

… benefits owing to possibly reversing the cytokine storm in patients with COVID-19 (38). …
in 484 patients with severe sepsis. Though the exact role of IL-1 in the pathogenesis of CSS is …

… released by the immune system in response to pathogenic material ( Figure 1 ). The … In
a study of 133 hematology patients receiving CAR-T, levels of both IL-6 and MCP-1 peaked …

… pathogenesis of progressive hypoxia in patients with COVID-19. While the initial results with
immune modulators are promising, the results of ongoing clinical trials will clarify the efficacy…