COVID-19: in the eye of the cytokine storm

R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
… It has been shown that aberrant pathogenic T cells and inflammatory monocytes are rapidly
… The authors suggest that the PLR of patients could be a proxy of the cytokine storm, since …

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
pathogenic organisms are capable of hyperstimulating the immune system, commonly known
as a cytokine storm. … Resistance in patients on long-term treatment regimens for recurrent …

Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents

S Khadke, N Ahmed, N Ahmed, R Ratts, S Raju… - Virology journal, 2020 - Springer
… Our knowledge of clinical manifestations and pathogenesis of COVID-19 is … 20 patients
with severe COVID-19, targeting cytokine storm demonstrated promising results, with 19 patients

Novel coronavirus disease 2019 (COVID-19) and cytokine storms for more effective treatments from an inflammatory pathophysiology

S Yokota, T Miyamae, Y Kuroiwa… - Journal of Clinical …, 2021 - mdpi.com
… , resulting in cytokine release syndrome or cytokine storm. … response and subsequent
cytokine storm in patients. First, … discuss the pathogenesis of cytokine storms associated with …

… cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine storm

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… in the alveoli, leading to a hyperinflammatory response in severely ill patients with … of
cytokine storm; hence, various mechanisms, immunological pathways, and functions of cytokines

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… the “cytokine storm”, the event occurring in those patients in … involved in the pathogenesis
of the cytokine storm, potentially … SARS-COV-2 infection-related cytokine storm and how their …

Quantification of cytokine storms during virus infections

S Yuan, SC Jiang, ZW Zhang, YF Fu, J Hu… - Frontiers in …, 2021 - frontiersin.org
pathogenic virus infections usually trigger cytokine storms, … For example, the H5N1 influenza
virus sets off a cytokine storm… SARS patients showed increased amounts of proinflammatory …

[HTML][HTML] Hypoxemia and cytokine storm in COVID-19: clinical implications

C Machado-Curbelo, A González-Quevedo - MEDICC review, 2022 - SciELO Public Health
cytokine storm pathogenesis is multifactorial, we hypothesize there is a close association
between hypoxemia and cytokine storms in … patients and thus avoid triggering a cytokine storm. …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
cytokines and pathways implicated in the pathogenesis of COVID-19-associated … cytokine
storm pathophysiology. Elevated levels of IL-6 may lead to multi-organ dysfunction in patients

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
… , in which inflammatory cytokines are rapidly secreted in a … cytokine storm is a severe status
observed in patients requiring … In these patients, the aberrant pathogenic T cells secrete …