… by elevated levels of pro-inflammatory cytokines, referred to as cytokinestorm. Interleukins, such as … Cytokinestorm is defined as acute overproduction and uncontrolled release of pro-…
LK Weaver, EM Behrens - Current treatment options in rheumatology, 2017 - Springer
… cytokinestorm syndromes, we outline a therapeutic approach that can be generalized across all forms of cytokinestorm, … drivers of disease pathogenesis for each type of cytokinestorm. …
… in the cytokine patterns, it seems that the cytokinestorm plays … types of pro-inflammatory cytokines and chemokines, which … called cytokinestorm. Both local tissue inflammation and the …
… The severe COVID-19 infection persuaded cytokinestorm that has been linked with acute respiratory distress syndrome (ARDS), culminates into vital organ failures and eventual death. …
L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
… cytokinestorms induced by COVID-19, as well as potential intervention strategies to control cytokinestorms. … This review will summarize research progress on cytokinestorms occurring …
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… cytokines initiate … cytokines involved. We also discuss the induction, function, downstream signaling, and existing and potential interventions for targeting these cytokines or related …
P Sinha, MA Matthay, CS Calfee - JAMA internal medicine, 2020 - jamanetwork.com
… Interventions targeting single cytokines in sepsis, unfortunately, also have a long history of failure. Although the term cytokinestorm conjures up dramatic imagery and has captured the …
… system dysregulation associated with CRS and acute respiratory distress syndrome in severe COVID-19 is imperative to identify novel drug targets and other therapeutic interventions. …
… has been suggested that a cytokinestorm of hyper-inflammation is … cytokinestorm. As this is not exclusive to COVID-19, we can learn much from known immuno-modulatory interventions…