Could SARS-CoV-2-induced hyperinflammation magnify the severity of coronavirus disease (CoViD-19) leading to acute respiratory distress syndrome?

ASS Girija, EM Shankar, M Larsson - Frontiers in immunology, 2020 - frontiersin.org
Cytokine storm likely could dampen innate and adaptive immune responses against
SARS-CoV-2 infection. Cytokine storm pathophysiology in CoViD-19 is often reported to be due to …

Critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis

S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
… induced through SARS-CoV-2 infection and mediated by excessive cytokine production and
… surge in several inflammatory cytokines following SARS-CoV-2 infection (cytokine storm/…

[HTML][HTML] Cytokine storm”, cytokine “breeze”, or both in COVID-19?

G Lippi, M Plebani - Clinical Chemistry and Laboratory Medicine …, 2021 - degruyter.com
… Nonetheless, despite the onset of a “cytokine storm” has hence been considered quite a
hallmark of SARS-CoV-2 infection, recent evidence would instead suggest that …

Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
… with SARS-CoV-2, the novel coronavirus implicated in COVID-19. Critically ill COVID-19
patients experiencing cytokine storm … In SARS-CoV-2 infected patients, cytokine storm appears …

Immune response resetting as a novel strategy to overcome SARS-CoV-2–induced Cytokine Storm

AE Nowill, PO de Campos-Lima - The Journal of Immunology, 2020 - journals.aai.org
… The resulting cytokine storm puts the immune system in overdrive at the expense of the
virus… enable and are shaped by the cytokine storm. Thus, SARS-CoV-2 infection is commonly …

Pathogenesis and treatment of cytokine storm in COVID-19

M Soy, G Keser, MP Atagündüz - Turkish Journal of Biology, 2021 - journals.tubitak.gov.tr
… In this respect, it is necessary to review briefly the pathogenesis of SARSCoV-2 infection …
SARS-CoV-2 may cause not only a cytokine storm where IL-1β and IL-18 play important roles, …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… Recently, Wenzhonget al. claimed that antimalarials might block the binding of the SARS
Cov-2 virus to porphyrins and thus prevent the entering of the virus to the cell [8]. Finally, they …

Targeting the catecholamine-cytokine axis to prevent SARS-CoV-2 cytokine storm syndrome

MF Konig, M Powell, V Staedtke, RY Bai, DL Thomas… - medRxiv, 2020 - medrxiv.org
Coronavirus disease 2019 (COVID-19), severe acute respiratory syndrome coronavirus 2
(SARS-CoV… of a cytokine storm syndrome (CSS) that resembles cytokine release syndrome (…

Atherosclerosis as pathogenetic substrate for Sars-Cov2 cytokine storm

M Vinciguerra, S Romiti, K Fattouch, A De Bellis… - Journal of Clinical …, 2020 - mdpi.com
… Referring to Sars-CoV similarities with the ACE2 structure, it … severe/critical manifestation of
Sars-CoV-2, the immunological … cytokine hosts in a cascade labeled a “cytokine storm” [7,9]. …

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… role of the so called “cytokine storm”, several studies were … in the pathogenesis of the cytokine
storm, potentially driving a … of the SARS-COV-2 infection-related cytokine storm and how …