… of the different cytokines involved. We also discuss the induction, function, … signaling, and
existing and potential interventions for targeting these cytokines or related signal pathways. We …

… PCD pathways: pyroptosis, apoptosis, and necroptosis; together, these pathways provide a
… We refer to the crosstalk between these cytokine-mediated inflammatory PCD pathways as ‘…

… immune responses of pathogenic Th1 cells and intermediate CD14 + CD16 + monocytes
are mediated by membrane-bound immune receptors and downstream signaling pathways. …

… The binding of TLRs occurs with the virus and may lead to the activation of NF-κB and
MAPK signaling pathways to facilitate viral clearance and produce antiviral responses. To …

… The IL-6 ‘classical’ pathway involves the IL-6 receptor (IL-6 R) which binds directly to gp130.
The ‘trans’ signaling pathway uses soluble sIL-6 receptors to aid gp130 binding and signal …

… cytokine storm is induced by the virus will be introduced in detail, including the ways in which
cytokines … NF-κB transcriptional signaling pathway and the binding site of the nuclear factor …

… The final activation sequence involves the NF-κB cross-talk with numerous cytokine and
TLR-mediated cell signalling pathways that depend upon the binding of TNFα and IL-1 to TLR4. …

… IL-6 is a kind of pro-inflammatory cytokine and there are two types of signaling pathways (classical
and trans signaling pathway) … In the classical pathway, IL-6 bind to its receptor ie mIL-…

… a cytokine storm and the biological consequences of cytokine overproduction. We will also
look at the cytokine storm … The redundancy of the cytokine and chemokine signaling pathways …

… (S1P 1 R) signaling is primarily responsible for blunting cytokine storm to protect the infected
… host innate signaling pathways of cytokine storm and chart where along those pathways the …