The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19

A Attiq, LJ Yao, S Afzal, MA Khan - International immunopharmacology, 2021 - Elsevier
… of life-threatening cytokine storm syndrome in advanced COVID-19 diseases. Coronavirus
hijacked NF-kappa B (NF-κB) is responsible for upregulating the expressions of inflammatory …

[HTML][HTML] Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy

Y Jiang, L Rubin, T Peng, L Liu, X Xing… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
syndrome (ARDS) caused by cytokine storm is a … cytokine storm is critical for reducing
mortality in severe COVID-19 patients. This review summarizes the mechanism of cytokine storm

Cytokine Storm and its Implication in Coronavirus disease 2019 (COVID-19)

C Datta, A Bhattacharjee - Journal of …, 2020 - immunologyresearchjournal.com
… known as severe acute respiratory syndrome corona virus 2 (… life threatening acute respiratory
distress syndrome (ARDS), … cytokine dysregulation resulting in “cytokine storm syndrome”…

Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?

D Panigrahy, MM Gilligan, S Huang, A Gartung… - Cancer and metastasis …, 2020 - Springer
cytokines (3) by immune cells such as macrophages, generating a robust “cytokine storm
that … (5) and subsequent acute respiratory distress syndrome. Tissue levels of SPMs and EETs …

[HTML][HTML] Cytokine storm and immunomodulatory therapy in COVID-19: role of chloroquine and anti-IL-6 monoclonal antibodies

M Zhao - International journal of antimicrobial agents, 2020 - ncbi.nlm.nih.gov
… Tocilizumab is a good therapeutic option for cytokine release syndrome in chimeric
antigen receptor T-cell immunotherapy. However, clinical experience with tocilizumab in viral …

The roles of neutrophils in cytokine storms

L Chan, N Karimi, S Morovati, K Alizadeh, JE Kakish… - Viruses, 2021 - mdpi.com
… pathogenesis of cytokine storms. … cytokine storm syndromes. Evidence for the destructive
potential of neutrophils in their capacity to contribute to the onset of cytokine storm syndromes is …

… in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome

O Halyabar, MH Chang, ML Schoettler… - Pediatric …, 2019 - Springer
… The result is a dramatic presentation in affected patients with fevers, rashes, multi-organ
dysfunction, cytopenias, and coagulopathy due to cytokine storm. The diagnosis of HLH is made …

Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
Cytokine storm, also referred to as cytokine release syndrome (CRS) or hyper-cytokine
syndrome [1]… However, the concept of cytokine storm is not limited to complications of coronavirus …

Cytokine storm and sepsis disease pathogenesis

BG Chousterman, FK Swirski, GF Weber - Seminars in immunopathology, 2017 - Springer
… the presence of a systemic inflammatory response syndrome (SIRS) and a proven or … ,
it clearly appears that this cytokine storm-induced syndrome is a major public health issue. …

Cytokine release syndrome in severe COVID-19

JB Moore, CH June - Science, 2020 - science.org
IL-6 is a key factor and culprit that triggers the "cytokine storm" and endothelial dysfunction,
which are responsible for the eventual catastrophic process, irrespective of the specific …