… ABSTRACT Cytokine storm has been proposed as the basis of the … Cytokine storm,
generally known as excessive or uncontrolled release of especially proinflammatory cytokines, …

… cytokines in a positive feedback loop of pathogen-triggered inflammation. Currently, cytokine
storm … Objective: The aim of this paper is to study the cytokine storm response in SARS-CoV-…

… cytokine release in response to viral infection, a condition known as cytokine release
syndrome (CRS) or cytokine storm… timed anti-inflammatory therapeutic strategies could improve …

… -2 mediated cytokine storm is associated with the mortality and morbidity of COVID-19 patients.
The key cytokines implicated in the onset of disease severity include TNF-α, IFN-γ, IL-6, IL…

… that release cytokines (notably IL-1, IL-6 and TNF) and … (cytokine storm) and tissue damage.
Some drugs have been studied as therapeutic targets (block to viral entry or to cytokine storm…

… , no effective therapeutic treatments or modalities have been developed to quell the
pathology associated with cytokine storm. In fact, the apparent intractability of tested therapies to …

… Multiple signaling pathways are activated during an immune response and cytokine storm.
The P2X purinoceptor 7 (P2X7r) is major factor involved in activation of the cytokine storm …

… , discuss immune dysregulation resulting in cytokine storm, and review immunomodulatory
options being studied in this disease. Therapeutic options are summarized in Table 1. …

… In this review, we provide a detailed insight into the cytokine storm … In addition, we discuss
the potential therapeutic agents that … the cytokine storm as an attractive therapeutic modality for …

… been suggested that a cytokine storm of hyper-inflammation is … therapies which target the
COVID-19 induced cytokine storm. … Virus-induced cytokine storm is associated with Secondary …