COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons

SH Nile, A Nile, J Qiu, L Li, X Jia, G Kai - Cytokine & growth factor reviews, 2020 - Elsevier
… One of the main features of ARDS is the cytokine storm - an uncontrolled systemic … -inflammatory
cytokines and chemokines by immune effector cells [5]. High blood levels of cytokines

Cytokine storm in COVID-19: Potential therapeutics for immunomodulation

MM Rana - Journal of Research in Clinical Medicine, 2020 - library.2pressrelease.co.in
… Another way to restrain the excessive level of cytokine signalling or cytokine storm is the
use of Janus kinase inhibitors (JAKi).Most JAK inhibitors are specifically effective at JAK1 and …

[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine stormstherapeutic

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… , do trigger life-threatening “cytokine storms” in the host which can … cytokine storms which
may prove useful in the clinic in the future and compare them to more traditional therapeutic

[PDF][PDF] Therapeutic potential of N-acetyl cysteine (NAC) in preventing cytokine storm in COVID-19: review of current evidence.

RR Mohanty, BM Padhy, S Das… - European Review for …, 2021 - europeanreview.org
… the use of NAC to review two key objectives, ie,: Therapeutic potential of NAC in decreasing
the immune activation and cytokine storm. Efficacy of NAC in management of COVID-19. We …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
… Articles found were assessed as potential reference sources. Also, we searched in … enrolling
potential therapeutic drugs related to pathophysiological mechanisms and cytokine storm. …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… is an urgent need to understand the cytokine storm in COVID-19. … cytokine storm induced
by COVID-19. In addition, we suggest that the identification and treatment of the cytokine storm

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
cytokine release in response to viral infection, a condition known as cytokine release
syndrome (CRS) or cytokine storm… timed anti-inflammatory therapeutic strategies could improve …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
… SARS-CoV-2 mediated cytokine storm is associated with the mortality and morbidity of
COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …

[HTML][HTML] Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
… identify the cytokine storm. In this review, we referred COVID-19 associated cytokine storm as
… patients who are severely ill along with a high concentration of pro-inflammatory cytokines. …