… Over-activity of chemotaxis triggers a macrophage activation syndrome (MAS) resulting
in the release of pro-inflammatory cytokines. IL-6 and TNF- α are at the forefront of hyper-…

… Additionally, recent developments in the comprehension of the so-called “cytokine storm”
in patients with severe COVID-19, hemophagocytic lymphohistiocytosis (HLH), and …

… inflammatory cytokines in patients with COVID-19, suggesting the existence of cytokine
storm in … in COVID-19 and the possible pathogenesis of cytokine storm induced by SARS-CoV-2. …

Severe COVID-19 cases are mostly due to severe inflammatory reaction and cytokine storm,
which may lead to multiple organ failure and death. Until recently, there is no proven …

… therapy, the rationale for the treatments that have been implemented for these syndromes,
and the prospect … no underlying malignancy, a robust cytokine storm was observed in 9 of the …

… in MSC therapy, its mode of action, cytokine storm, and challenges faced by COVID-19. …
therapeutics. Key cytokines with frequently high levels in cytokine storm include interferon-γ, IL-1, …

… as a source for valuable anti-inflammatory therapeutic compounds. As a matter of fact,
microalgae indeed have interesting prospects as they represent a diverse origin of chemically …

… So the above outcome would prospect towards rationalized purposing of Remdesivir in …
Such outcomes create a limiting factor and barrier on clinical prospect and translation of these …

… EVs derived from various cellular origins have revealed suppressive effects on the cytokine
storm during systemic hyper-inflammatory states of severe COVID-19, leading to enhanced …

… cytokines (IFN-α, TNF-γ, IL-1β, IL-6, IL-12, IL-8, IL-33, and TGF-β) [53]. The mechanism of
the cytokine storm … As a result of the cytokine storm, the patient develops acute respiratory …