Viral load and cytokine response profile does not support antibody-dependent enhancement in dengue-primed Zika virus–infected patients

ACB Terzian, AS Schanoski, MTO Mota… - Clinical Infectious …, 2017 - academic.oup.com
… , IL-8, IL-9, IL-10, IL-13, and IL-17 was used to analyze the levels of circulating cytokines in
patients exposed to a second infection. These cytokines are involved in the “cytokine storm” …

Disruption of the CCL5/RANTES-CCR5 pathway restores immune homeostasis and reduces plasma viral load in critical COVID-19

BK Patterson, H Seethamraju, K Dhody, MJ Corley… - MedRxiv, 2020 - medrxiv.org
… Indeed, excessive immune cell infiltration into the lung, cytokine storm, and ARDS have
previously … trafficking of pro-inflammatory leukocytes and reverse cytokine storm in COVID-19. …

The cytokine storm in COVID-19: the strongest link to morbidity and mortality in the current epidemic

M Basheer, E Saad, N Assy - COVID, 2022 - mdpi.com
cytokine storm due to the SARS-CoV-2 virus infection results in an excessive inflammatory
reaction with the release of large amounts of pro-inflammatory cytokines (… to the viral load but …

Fighting cytokine storm and immunomodulatory deficiency: By using natural products therapy up to now

MA Mohammed - Frontiers in Pharmacology, 2023 - frontiersin.org
… for fighting cytokine storms and immunomodulatory deficiency induced by COVID-19
using natural product therapy as a potential therapeutic measure to control cytokine storms. …

Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care

L Quartuccio, A Sonaglia, D McGonagle… - Journal of Clinical …, 2020 - Elsevier
… Very recently, IL-6 serum levels were also closely correlated with viral load in critically ill …
group received anti-viral agents [17]. Notably, baseline CRP and IL-6 continued to distinguish …

[PDF][PDF] Cytokine Storm syndrome in COVID-19 patients: Characteristics And diagnosis

RM Harfouch - Ann Clin Med Case Rep, 2021 - researchgate.net
… The cytokine storm in COVID-19 may have some differences from the cytokine storms in
other clinical settings. Remarkably, the autopsy findings revealed that the lymphoid tissues and …

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
cytokine storm; and failure of host protective immunity that results in unrestrained viral
dissemination … Approximately 25% of COVID-19 patients had increased IL-6 levels that were not …

Silibinin and SARS-CoV-2: dual targeting of host cytokine storm and virus replication machinery for clinical management of COVID-19 patients

J Bosch-Barrera, B Martin-Castillo, M Buxó… - Journal of clinical …, 2020 - mdpi.com
… -JAK1/2 inhibitors to limit the cytokine storm and T-cell … viral load and impede delayed
interferon responses. The dual ability of silibinin to target both the host cytokine storm and the virus

Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome

P Mehta, RQ Cron, J Hartwell, JJ Manson… - The Lancet …, 2020 - thelancet.com
… In cytokine storm syndromes, the subcutaneous route is often … in the management of cytokine
storm syndromes and review the … improve the poor prognosis of cytokine storm syndromes. …

Resolution of viral load in mild COVID-19 patients is associated with both innate and adaptive immune responses

A Anantharaj, S Gujjar, N Verma, NA Khan… - Journal of Clinical …, 2022 - Elsevier
cytokine storm has been implicated in clinical manifestations observed in severe disease
[6, 7, 8]. Increased viral load … such as remdesivir which inhibit the viral RNA-dependent-RNA-…