[HTML][HTML] Autoinflammatory diseases and cytokine storms—imbalances of innate and adaptative immunity

A Marcuzzi, E Melloni, G Zauli, A Romani… - International Journal of …, 2021 - mdpi.com
immune system and shows a clinical phenotype characterized by alternating periods of
exacerbation and remission [1]. It is known that innate and adaptive immune … the immune system …

[HTML][HTML] Cytokine storms in infectious diseases

JR Teijaro - Seminars in immunopathology, 2017 - Springer
… The immune system secretes soluble mediators to instruct both innate and adaptive immune
… Clark and Vissel review the history of cytokine storm and highlight the roles cytokines play …

[HTML][HTML] Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… human innate and adaptive immune systems consist of effector cells producing cytokines
(… chain reactions resulting in a massive release of cytokines. This may result in a drastic self-…

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - … Vaccine Immunology, 2013 - Am Soc Microbiol
… It is responsible for activating both innate and adaptive immune responses so that the
damage can be resolved and homeostasis restored. The characteristic signs of inflammation …

[HTML][HTML] Innate and adaptive immune responses against coronavirus

A Hosseini, V Hashemi, N Shomali, F Asghari… - Biomedicine & …, 2020 - Elsevier
… The immune responses (innate and adaptive immunity) are … , however, uncontrolled
immune responses can result in … Given IL-6 plays a critical role in cytokine storm, IL-6 receptor …

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… In addition to quantitating circulating pro- and antiinflammatory cytokines, we evaluated
adaptive and innate immune systems via serial ELISpot assays of T cell IFN-ɣ and monocyte …

Mesenchymal stem cells-bridge catalyst between innate and adaptive immunity in COVID 19

V Rao, S Thakur, J Rao, G Arakeri, PA Brennan… - Medical …, 2020 - Elsevier
… dysfunctional bridge adaptive immunity, the innate immune response becomes exaggerated
due to the lack of feedback from the adaptive immune cells. The resultant cytokine storm is …

Immune-mediated cytokine storm and its role in severe dengue

A Srikiatkhachorn, A Mathew, AL Rothman - Seminars in …, 2017 - Springer
… , especially cytokines and … innate and adaptive immune responses. In this article, we review
current understanding of events leading to the induction of the innate and adaptive immune

Underlying vulnerabilities to the cytokine storm and adverse COVID-19 outcomes in the aging immune system

LS Nidadavolu, JD Walston - The Journals of Gerontology …, 2021 - academic.oup.com
… of innate immune system activation and adaptive immune system dysregulation in older
adults and how they potentiate the consequences of the COVID-19-related cytokine storm, and …

[HTML][HTML] Not so fast: adaptive suppression of innate immunity

NW Palm, R Medzhitov - Nature medicine, 2007 - nature.com
innate and adaptive immune responses 7 and are the obvious candidates for the suppressors
of the lethal cytokine storm… (I:C)-induced cytokine production by cells of the innate immune