Cytokines and chemokines in SARS-CoV-2 infections—therapeutic strategies targeting cytokine storm

A Pum, M Ennemoser, T Adage, AJ Kungl - Biomolecules, 2021 - mdpi.com
Cytokine storm and the often-resulting cytokine release … event, chemokines and other cytokines
are highly upregulated … the involvement of chemokines and selected cytokines in COVID-…

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
SARS-CoV and SARS-CoV-2 might differ in their ability to modulate the production of pro-…
cytokines and chemokines. As an example, it could be worth highlighting that SARS-CoV

The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
… on cytokine and chemokine secretions induced by host immune responses in COVID-19 as
well as on cytokine … To further illustrate the effect of SARS-CoV-2 on cytokine and chemokine

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
… In the short time since the emergence of COVID-19, numerous studies have described
abnormal levels of the following cytokines and chemokines in the patients: IL-1, IL-2, IL-4, IL-6, IL-…

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARSCoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
… test panel were utilized to determine the early-stage effects of SARS-CoV-2 on cytokine
and chemokine output. According to the updated studies on the severity of COVID-19, the …

[HTML][HTML] Immune environment modulation in pneumonia patients caused by coronavirus: SARS-CoV, MERS-CoV and SARS-CoV-2

Z Yao, Z Zheng, K Wu, Z Junhua - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
cytokines and chemokines, which are similar to the symptoms of SARS-CoV and MERS-CoV
of SARS-CoV and MERS-CoV still can give us a lot of information on the pathogenesis of …

Comparison of the characteristics of cytokine storm and immune response induced by SARS-CoV, MERS-CoV, and SARS-CoV-2 infections

T Liu, M Feng, Z Wen, Y He, W Lin… - Journal of Inflammation …, 2021 - Taylor & Francis
… with SARS-CoV, it leads to a surge in cytokines and chemokines, which plays a vital role in
the pathogenesis of CS in patients with SARSSARS-CoV does not have the ability to attack T …

Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2

CM Su, L Wang, D Yoo - Scientific reports, 2021 - nature.com
… These cytokines and chemokines are frequently elevated in severely affected COVID-19 …
into how SARS-CoV-2 modulates NF-κB response and inflammatory cytokines expression. Our …

Immune responses to SARS-CoV, MERS-CoV and SARS-CoV-2

N İnandıklıoğlu, T Akkoc - Cell Biology and Translational Medicine, Volume …, 2020 - Springer
… , SARS-CoV-infected patients have an increase in chemokine IL-… The determination of
cytokine/chemokine profiles with … responses between MERS-CoV and SARS-CoV infections. In …

Association between the expression of toll-like receptors, cytokines, and homeostatic chemokines in SARS-CoV-2 infection and COVID-19 severity

W Alturaiki, H Alkadi, S Alamri, ME Awadalla, A Alfaez… - Heliyon, 2023 - cell.com
cytokines, homeostatic chemokines and SARS-CoV-2 IgG and IgM levels … of cytokines
and homeostatic chemokines in SARS-CoV-2-infected ICU-admitted patients (n = 50); SARS-CoV-…