Cytokines in sepsis: friend or enemy?

SR Senousy, AS Ahmed, M El-Daly… - Journal of advanced …, 2022 - journals.ekb.eg
… of pro-inflammatory cytokines promotes survival in animal models of sepsis, yet, such a …
of the cytokine storm during sepsis and represent in detail the role of cytokines responsible for …

[HTML][HTML] Adrenomedullin in sepsis: finally, a friend or an enemy?

AKA Kumar - Indian Journal of Critical Care Medicine: Peer …, 2020 - ncbi.nlm.nih.gov
… interactions with other cytokines released in the sepsis cascade. Being a multifunctional
hormone, its action in other tissues could also affect the net clinical effects of septic shock. Finally…

Dual effects of tumor necrosis factor α inhibitors on septic arthritis: from a “bad friend” to a “good enemy

SI Lee, WU Kim - Arthritis & Rheumatology, 2015 - Wiley Online Library
… A range of studies using experimental models of septic arthritis showed that T cells and their
cytokines, including interleukin-17 (IL-17), are clearly involved in septic arthritis (7). This is …

When our best friend becomes our worst enemy: The mitochondrion in trauma, surgery, and critical illness

MK Torp, KO Stensløkken… - Journal of Intensive Care …, 2024 - journals.sagepub.com
sepsis, 92 and sepsis-induced levels were higher than those caused by surgery alone.
Elevated levels of mtDNA in human sepsis … pro-inflammatory cytokines. These investigators also …

The role of immunocytes in acute and chronic pancreatitis: when friends turn into enemies

HG Beger, F Gansauge, JM Mayer - Gastroenterology, 2000 - Elsevier
… In acute pancreatitis, although late sepsis-related deaths resulting from … cytokines in early
acute pancreatitis has been found to predict severity, 24 and lymphocyte-associated cytokines

Dangers, and benefits of the cytokine mediated response to injury and infection

PB Soeters, RF Grimble - Clinical nutrition, 2009 - Elsevier
… and even more so in severe infection (sepsis) as much as 5–10 l … sepsis generate similar
responses, the response after sepsis … Inflammation is both a friend and an enemy in the survival …

[HTML][HTML] New paradigms in sepsis: from prevention to protection of failing microcirculation

J Hawiger, RA Veach, J Zienkiewicz - Journal of Thrombosis and …, 2015 - Elsevier
… Recombinant Slit protein increased survival in polymicrobial sepsis whereas cytokines
remained elevated. Similarly, selective targeting of transcription factor nuclear factor kappa B (NF‐…

Scientific and clinical challenges in sepsis

L Ulloa, M Brunner, L Ramos… - Current pharmaceutical …, 2009 - ingentaconnect.com
… of sepsis by directly regulating cytokine production through the proteolytic processing of
cytokine … in caspases can alter the production of cytokines. For example, a well documented …

[HTML][HTML] Keep your friends close, but your enemies closer: Role of acid sphingomyelinase during infection and host response

HY Chung, RA Claus - Frontiers in Medicine, 2021 - frontiersin.org
… an exaggerated response to polymicrobial sepsis with an increased bacterial burden, an
enhanced phagocytotic activity, a more pronounced cytokine storm and decreased survival rate …

The immune response in critical illness: excessive, inadequate or dysregulated

JL Vincent - Immune Response in the Critically Ill, 2002 - Springer
… thought of as an enemy, the septic response is, in fact, as much a friend, a normal and …
sepsis response. TNF was the first pro-inflammatory cytokine to be identified in the blood of septic