[HTML][HTML] Histamine release theory and roles of antihistamine in the treatment of cytokines storm of COVID-19

OA Eldanasory, K Eljaaly, ZA Memish… - Travel medicine and …, 2020 - ncbi.nlm.nih.gov
… to cytokine storm and multi-organs failure. Thus, the use of antihistaminic medications could
result in a significant immune modulation which may help in the treatment of cytokine storm

[HTML][HTML] Cytokine storm syndrome in SARS-CoV-2 infections: a functional role of mast cells

B Hafezi, L Chan, JP Knapp, N Karimi, K Alizadeh… - Cells, 2021 - mdpi.com
treatments that should be administered [1,2]. An important and difficult distinction that is
required to properly treat cytokine storm … clinical trials that antihistamines exert limited short-term …

[HTML][HTML] Antihistamines as an early treatment for Covid-19

JIM Blanco, JAA Bonilla, P Fremont-Smith… - Heliyon, 2023 - cell.com
cytokines, leading to the dreaded cytokine storm and ARDS aggravation. Several antihistamines
… on the production and expression of interleukins, chemokines, and other cytokines [ …

[PDF][PDF] Anti-histamines and Covid-19: hype or hope

HM Al-Kuraishy, HF Al-Rubiey… - JPMA J Pak Med …, 2021 - researchgate.net
Antihistamine drugs are effective in the treatment and … Taken together, hospitalised Covid-19
patients treated with … It plays an important role in the chemotaxis and cytokine storm during …

Dual-histamine receptor blockade with cetirizine-famotidine reduces pulmonary symptoms in COVID-19 patients

RB Hogan II, RB Hogan III, T Cannon, M Rappai… - Pulmonary …, 2020 - Elsevier
… Syndrome as a result of a pulmonary cytokine storm. Antihistamines are safe and effective
treatments for reducing inflammation and cytokine release. Combinations of Histamine-1 and …

[HTML][HTML] Massive release of TH2 cytokines induced a cytokine storm during a severe mast cell activation event in a patient with indolent systemic mastocytosis

T Boehm, R Ristl, J Mühlbacher, P Valent… - Journal of Allergy and …, 2022 - Elsevier
… release syndrome because the 3 criteria of the latest definition of a cytokine storm were …
Consequently, without antihistamine treatment, the strongly elevated T H 2 cytokines might have …

Therapeutic uses of Antihistamines in the Management of COVID-19: A Narrative Review

M Ataei, O Arasteh, AS Maghsoudi… - Anti-Infective …, 2023 - ingentaconnect.com
… its symptoms, including anosmia, ageusia, and cytokine storm, are dependent on the release
of … be effective in treating and improving the symptoms of COVID-19 is antihistamines. This …

[HTML][HTML] Combinational benefit of antihistamines and remdesivir for reducing SARS-CoV-2 replication and alleviating inflammation-induced lung injury in mice

ML Wu, FL Liu, J Sun, X Li, JR Qin, QH Yan… - Zoological …, 2022 - ncbi.nlm.nih.gov
… of cells for 20 min at 4 C before intracellular cytokine staining. Rat anti-human IL-6-PE (BD,
MQ2-… In our study, early combined treatment with the antihistamine loratadine and remdesivir …

Antihistamines as an early treatment for Covid-19

P Fremont-Smith - Heliyon, 2023 - europepmc.org
cytokines, leading to the dreaded cytokine storm and ARDS aggravation. Several antihistamines
… and expression of interleukins, chemokines, and other cytokines [11]. This suggests that …

The histamine-cytokine network in allergic inflammation

G Marone, F Granata, G Spadaro, A Genovese… - Journal of allergy and …, 2003 - Elsevier
… to propose antihistamines be used to treat bronchial asthma. However, early antihistamines
… Several studies have looked at the effects of antihistamines on histamine and methacholine …