… The vectorial secretion of effector T-cells is well documented and will be reviewed in this
chapter for both cytotoxic and helper cells. EFFECTOR· TARGET INTERACTION …

… cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-
dependent cytotoxicity … to modulate antibodies' effector functions. Strategies in modifying the …

… cytotoxicity against MHC class I-deficient target cells, including tumor cells and their metastases
in vivo [2], [5]. NK cell effector functions, including their cytotoxicity … of cytotoxic granules, …

… vivo activation or expansion of cytotoxic lymphocytes, or various … cytotoxic activities of these
cells remain unanswered, especially regarding the mechanisms controlling cytotoxic effector …

… cytotoxic effector function as a consequence of increased IL2 production. More … and, thereby,
up-regulates IL2 secretion and cytotoxic effector function. In contrast to findings in mice (9), …

… Cytotoxic T-lymphocytes (CTL) appear to play the most … The various cytotoxic effector cells
differ distinctly concerning … which are not present in other cytotoxic cells. LAK cells constitute …

… agents, may have more subtle modulatory functions. Because cytotoxic effector molecules
such as TNF and LT may have modulatory activity on other cell functions (24-271, secretion of …

Background There is mounting evidence that perforin and granzymes are important mediators
in the lung destruction seen in COPD. We investigated the characteristics of the three …

… biology and the mechanisms of action of cytotoxic antitumor antibodies as well as newer …
to mediate their effector functions. New data demonstrating that cytotoxic antitumor antibodies …

… help to CD8-mediated cytotoxic effector function is not clear, … CD8 + cytotoxic T lymphocytes
(CTL) effector function is … suggest that the enhanced cytotoxic effector activity generated in …