A Kamdar, R Sykes, A Morrow… - Reviews in …, 2021 - eprints.gla.ac.uk
… DAPA-CKD trial was discontinued by the data monitoring committee when an interim analysis … Further trials with prespecifiedanalysis would be required to establish this finding fully. …
T Sen, R Scholtes, PJ Greasley, D Cherney… - Diabetes, obesity & …, 2022 - ncbi.nlm.nih.gov
… The analyses of the DAPASALT study were pre-specified and the analyses of the DIAMOND … In summary, SGLT2 inhibitor dapagliflozin decreased blood pressure despite no clear …
… In conclusion, the pre-specifiedanalysis of the DAPA-CKD trial has confirmed that … of an abrupt decline in kidney function in patients with CKD. Although further studies are needed to …
M Borkum, A Levin - Canadian Journal of General Internal …, 2022 - utpjournals.press
… studies (CREDENCE, DAPA and EMPA CKD, the latter of … analysis of DAPA-CKD showed no significant interaction of treatment effects (including efficacy and safety outcomes) by CKD …
Q Tan, H Xue, X Ni, L Fan, W Du - European Journal of Internal Medicine, 2023 - Elsevier
… In addition, the DAPA-CKD study did not adopt 24 h … hence we considered this population in DAPA-CKD to be eligible for … A pre-specifiedanalysis of the DAPA-CKD trial demonstrates …
… The DAPA-CKD subgroup analysis included a group of patients with IgAnephropathy and another with focal segmental glomerulosclerosis (FSGS). There were 270 subjects with …
…, DAPA‐HF Investigators and Committees - European journal of …, 2021 - Wiley Online Library
… therapy) and the pre-specified secondary endpoints of total … summary score (OSS) and clinical summary score (CSS). … In this post-hoc analysis of DAPA-HF we found that anaemia …
C Loutradis, P Sarafidis - Expert Opinion on Pharmacotherapy, 2020 - Taylor & Francis
… In the pre-specified renal outcome analysis, the benazepril-amlodipine group was shown to have a slower decrease in eGFR rate (−0.88 vs −4.22 mL/min/1.73m 2 per year) although it …
M Brockmeyer, C Parco, KG Vargas, R Westenfeld… - Journal of …, 2024 - Springer
… a pre-specified … in DAPA-HF [11, 27] (2-year meta-number needed to treat of 21) and EMPEROR-REDUCED [12, 27] (2-year meta-number needed to treat of 15), the present analysis …