Effects of Dapagliflozin in Chronic Kidney Disease, With and Without Other Cardiovascular Medications: DAPA‐CKD Trial

…, DAPA‐CKD Trial Committees and … - Journal of the …, 2023 - Am Heart Assoc
… The DAPA‐CKD trial required that all patients be treated … DAPA‐CKD trial, we aimed to
examine whether baseline use of cardiovascular medications modified the effects of dapagliflozin

… dapagliflozin on the rate of decline in kidney function in patients with chronic kidney disease with and without type 2 diabetes: a prespecified analysis from the DAPA …

HJL Heerspink, N Jongs, GM Chertow… - The lancet Diabetes & …, 2021 - thelancet.com
… In this prespecified analyses of the DAPA-CKD trial, we assessed the effect of dapagliflozin
on eGFR slope by establishing the effect of dapagliflozin on changes in eGFR during the …

Extrapolating long-term event-free and overall survival with dapagliflozin in patients with heart failure and reduced ejection fraction: an exploratory analysis of a phase …

KF Docherty, PS Jhund, B Claggett, JP Ferreira… - JAMA …, 2021 - jamanetwork.com
DAPA-HF, we used previously described methods to enable estimation of the projected
long-term treatment effects of dapagliflozin … treatment effect of dapagliflozin compared with …

Time to clinical benefit of dapagliflozin and significance of prior heart failure hospitalization in patients with heart failure with reduced ejection fraction

DD Berg, PS Jhund, KF Docherty, SA Murphy… - JAMA …, 2021 - jamanetwork.com
… , we examined the timing of onset of clinical benefit with dapagliflozin in the DAPA-HF trial. …
In this analysis from the DAPA-HF trial, we found that the clinical benefit of dapagliflozin for …

Cost‐effectiveness of dapagliflozin for patients with heart failure across the spectrum of ejection fraction: A pooled analysis of DAPAHF and DELIVER data

JA Davis, D Booth, P McEwan… - European Journal of …, 2024 - Wiley Online Library
… was observed across the broad range of LVEF for CVM and hospitalization for HF (HHF). To
… from the DAPA-HF and DELIVER trials to explore the cost-effectiveness of dapagliflozin as a …

Effects of dapagliflozin in stage 4 chronic kidney disease

GM Chertow, P Vart, N Jongs, RD Toto… - Journal of the …, 2021 - journals.lww.com
… In this prespecified subgroup analysis of the DAPA-CKD trial, we show beneficial effects
of dapagliflozin on kidney and cardiovascular end points in patients with stage 4 CKD at …

[HTML][HTML] Heart failure, investigator-reported sleep apnea and dapagliflozin: A patient-level pooled meta-analysis of DAPA-HF and DELIVER

JH Butt, K Jering, RA de Boer, BL Claggett… - Journal of Cardiac …, 2024 - Elsevier
… outcomes and the effects of dapagliflozin in patients with HF with and without sleep apnea
in a pooled analysis of 2 trials comparing dapagliflozin to placebo in HFrEF (DAPA-HF trial) …

Efficacy and safety of dapagliflozin by baseline glycemic status: a prespecified analysis from the DAPA-CKD trial

F Persson, P Rossing, P Vart, GM Chertow… - Diabetes …, 2021 - Am Diabetes Assoc
… In this prespecified analysis of the DAPA-CKD trial, we demonstrate that the effects of
dapagliflozin on kidney failure, heart failure, and mortality outcomes were consistent regardless of …

Cost Effectiveness of Dapagliflozin for Heart Failure Across the Spectrum of Ejection Fraction: An Economic Evaluation Based on Pooled, Individual Participant Data …

AS Bhatt, M Vaduganathan, BL Claggett… - Journal of the …, 2024 - Am Heart Assoc
… individual participant‐level data from DELIVER and DAPAHF, we found that the addition
of dapagliflozin to standard of care in patients with HF across the full spectrum of EF was of …

The effect of dapagliflozin on ventricular arrhythmias, cardiac arrest, or sudden death in people with heart failure: a tick in another box for sodium-glucose …

T Koufakis, G Giannakoulas, P Zebekakis… - Expert Opinion on …, 2022 - Taylor & Francis
… In conclusion, the findings of the post hoc analysis of DAPA-HF that demonstrate a positive
effect of dapagliflozin on the composite outcome of any serious VA, resuscitated cardiac arrest…