The Dapagliflozin and Prevention of Adverse‐outcomes in Heart Failure (DAPAHF) trial: baseline characteristics

…, DAPAHF Committees and Investigators - … of heart failure, 2019 - Wiley Online Library
DAPA-HF were similar to those in other contemporary HF with reduced ejection fraction (HFrEF)
registries and trials. … Consequently, DAPA-HF will test the incremental efficacy and safety …

SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials

F Zannad, JP Ferreira, SJ Pocock, SD Anker, J Butler… - The Lancet, 2020 - thelancet.com
… Using study-level published data from DAPA-HF and patient-… on fatal and non-fatal heart
failure events and renal outcomes in … subgroups from DAPA-HF and EMPEROR-Reduced trials. …

Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF

PS Jhund, SD Solomon, KF Docherty, HJL Heerspink… - Circulation, 2021 - Am Heart Assoc
… of Adverse-outcomes in Heart Failure), the SGLT2 inhibitor … cardiovascular death or worsening
heart failure (HF) in patients who had HFrEF with and without type 2 diabetes. In this study

Dapagliflozin and diuretic use in patients with heart failure and reduced ejection fraction in DAPA-HF

AM Jackson, P Dewan, IS Anand, J Bělohlávek… - Circulation, 2020 - Am Heart Assoc
… benefits of dapagliflozin in DAPA-HF were obtained regardless of … DAPA-HF was in keeping
with other reports in large cohorts of patients with HFrEF, predominantly in New York Heart

Effect of dapagliflozin in patients with HFrEF treated with sacubitril/valsartan: the DAPA-HF trial

SD Solomon, PS Jhund, BL Claggett, P Dewan… - Heart failure, 2020 - jacc.org
DAPA-HF, we could not directly assess the potential incremental value of treatment with both
dapagliflozin and sacubitril/valsartan in this trial… PARADIGM-HF and DAPA-HF trials was on …

Effects of dapagliflozin on symptoms, function, and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial

MN Kosiborod, PS Jhund, KF Docherty, M Diez… - Circulation, 2020 - Am Heart Assoc
study, which evaluated prespecified assessments of health status using KCCQ in the DAPA-HF
trial… composite end point of cardiovascular death or worsening HF, and its components, to …

Dapagliflozin and new-onset type 2 diabetes in patients with chronic kidney disease or heart failure: pooled analysis of the DAPA-CKD and DAPA-HF trials

P Rossing, SE Inzucchi, P Vart, N Jongs… - The Lancet Diabetes & …, 2022 - thelancet.com
… exploratory endpoint in both DAPA-CKD and DAPA-HF trials and is the focus of this
analysis. New-onset type 2 diabetes was identified by serial trial measurements of HbA 1c (two …

Dapagliflozin and recurrent heart failure hospitalizations in heart failure with reduced ejection fraction: an analysis of DAPA-HF

PS Jhund, P Ponikowski, KF Docherty, SB Gasparyan… - Circulation, 2021 - Am Heart Assoc
failure (HF) in patients with heart failure and reduced ejection fraction (HFrEF). In this analysis
of DAPA-HF, … secondary end point of total failure hospitalizations (first and recurrent) and …

Effects of dapagliflozin in DAPA-HF according to background heart failure therapy

KF Docherty, PS Jhund, SE Inzucchi… - European heart …, 2020 - academic.oup.com
… the DAPA-HF trial, the SGLT2 inhibitor dapagliflozin reduced the risk of worsening heart
failure (HF) and death in patients with HF … was consistent in relation to background HF therapy. …

Effect of dapagliflozin according to baseline systolic blood pressure in the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure trial (DAPA-HF)

M Serenelli, M Böhm, SE Inzucchi, L Køber… - European heart …, 2020 - academic.oup.com
Study outcomes … of an episode of worsening heart failure (HF hospitalization or an urgent
visit because of worsening HF requiring intravenous therapy) or cardiovascular (CV) death, …