Atrial fibrillation and dapagliflozin efficacy in patients with preserved or mildly reduced ejection fraction

JH Butt, T Kondo, PS Jhund, J Comin-Colet… - Journal of the American …, 2022 - jacc.org
… This study examined the effects of dapagliflozin according to the presence … heart disease,
and elevated N-terminal pro–B-type natriuretic peptide levels were randomized to dapagliflozin

Efficacy of dapagliflozin according to geographic regions in patients with heart failure: a patient-level pooled analysis of DAPA-HF and DELIVER

T Kondo, V Vaduganathan, AF Hernandez… - European Heart …, 2023 - academic.oup.com
… LVEF similarly across all regions studied (Figure 1). The benefit of dapagliflozin on the
primary outcome was not modified by region: hazard ratio for dapagliflozin versus placebo 0.85 (…

[HTML][HTML] Dapagliflozin in patients with heart failure and reduced ejection fraction

JJV McMurray, SD Solomon, SE Inzucchi… - … England Journal of …, 2019 - Mass Medical Soc
Heart Association class II, III, or IV heart failure and an ejection fraction of 40% or less to receive
either dapagliflozin (at … The primary outcome was a composite of worsening heart failure (…

[HTML][HTML] Effect of dapagliflozin in patients with heart failure: A systematic review and meta-analysis

AE Ali, MS Mazroua, M Elsaban, N Najam… - Global Heart, 2023 - ncbi.nlm.nih.gov
study, which was designed to study the effect of dapagliflozin … Hence, further studies
investigating the effects of dapagliflozin in … in our study was as low as 27.2 in the dapagliflozin

Baseline characteristics of patients with HF with mildly reduced and preserved ejection fraction: DELIVER trial

SD Solomon, M Vaduganathan, BL Claggett… - Heart Failure, 2022 - jacc.org
DELIVER is a global randomized, double-blind, parallel-… of dapagliflozin with placebo in
patients with heart failure (HF) … financial support for the DELIVER study from AstraZeneca; …

Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF

PS Jhund, SD Solomon, KF Docherty, HJL Heerspink… - Circulation, 2021 - Am Heart Assoc
… outcome of cardiovascular death or worsening heart failure (HF) in … In this study, we explored
whether the effect of dapagliflozin … We also examined the effect of dapagliflozin on kidney …

Efficacy and safety of dapagliflozin in men and women with heart failure with reduced ejection fraction: a prespecified analysis of the dapagliflozin and prevention of …

JH Butt, KF Docherty, MC Petrie, M Schou… - JAMA …, 2021 - jamanetwork.com
Dapagliflozin in patients with heart failure and reduced ejection fraction.  … In this study,
sex modified the effect of dapagliflozin on the mean change in KCCQ-TSS from baseline to 8 …

Projected clinical benefits of dapagliflozin in patients with heart failure with preserved ejection fraction

M Montero-Pérez-Barquero… - Future …, 2023 - Taylor & Francis
… In our study, the mean age was 81 years, and 59% of patients were women. In the DELIVER
trial, the benefits of dapagliflozin were independent of age or sex, emphasizing its use in all …

[HTML][HTML] Eligibility for dapagliflozin and empagliflozin in a real-world heart failure population

T Thorvaldsen, G Ferrannini, L Mellbin, L Benson… - … of Cardiac Failure, 2022 - Elsevier
… , in a real-word heart failure population. Our results from the Swedish Heart Failure
Registry show that a great number of patients with heart failure might be candidates for these …

Estimated event-free survival benefits with dapagliflozin in HF with mildly reduced or preserved ejection fraction

M Vaduganathan, BL Claggett, P Jhund… - Journal of the …, 2022 - eprints.gla.ac.uk
… OBJECTIVES This studyHeart Failure) trial, using previously validated actuarial methods,
we extrapolated the potential gains in event-free survival from long-term use of dapagliflozin in …