Effects of dapagliflozin in DAPA-HF according to background heart failure therapy

KF Docherty, PS Jhund, SE Inzucchi… - European heart …, 2020 - academic.oup.com
… the DAPA-HF trial, the SGLT2 inhibitor dapagliflozin reduced the risk of worsening heart
failure (HF) and death in patients with HF … was consistent in relation to background HF therapy. …

The Dapagliflozin and Prevention of Adverse‐outcomes in Heart Failure (DAPAHF) trial: baseline characteristics

…, DAPAHF Committees and Investigators - … of heart failure, 2019 - Wiley Online Library
… Association functional class ≥ II, a left ventricular ejection fraction ≤ 40%, an elevated N-…
DAPA-HF, which is comparing dapagliflozin 10 mg once daily to matching placebo. In patients

Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF

PS Jhund, SD Solomon, KF Docherty, HJL Heerspink… - Circulation, 2021 - Am Heart Assoc
… We have reported that the benefits of dapagliflozin on cardiovascular outcomes were
consistent in patients with and without type 2 diabetes in DAPA-HF. The current data extend these …

Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER

PS Jhund, T Kondo, JH Butt, KF Docherty… - Nature medicine, 2022 - nature.com
… There was a significant benefit of dapagliflozin on death from CV causes in DAPA-HF (HR …
Using the pooled analysis of DAPA-HF and DELIVER, the number of patients with HF who …

Effect of dapagliflozin according to baseline systolic blood pressure in the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure trial (DAPA-HF)

M Serenelli, M Böhm, SE Inzucchi, L Køber… - European heart …, 2020 - academic.oup.com
… in patients with heart failure and … of dapagliflozin, which lowers systolic blood pressure
(SBP),according to baseline SBP in Dapagliflozin and Prevention of Adverse Outcomes in Heart

Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to age: insights from DAPA-HF

FA Martinez, M Serenelli, JC Nicolau, MC Petrie… - Circulation, 2020 - Am Heart Assoc
… of mortality and heart failure hospitalization and improved symptoms in patients with heart
failure and reduced ejection fraction. We examined the effects of dapagliflozin according to …

Effects of dapagliflozin on symptoms, function, and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial

MN Kosiborod, PS Jhund, KF Docherty, M Diez… - Circulation, 2020 - Am Heart Assoc
… The beneficial effects of dapagliflozin on heart failure … indicate that dapagliflozin significantly
improves heart failure–… by the Kansas City Cardiomyopathy Questionnaire, with the benefits …

Dapagliflozin and diuretic use in patients with heart failure and reduced ejection fraction in DAPA-HF

AM Jackson, P Dewan, IS Anand, J Bělohlávek… - Circulation, 2020 - Am Heart Assoc
… The key finding of the present analyses is that the benefits of dapagliflozin in DAPA-HF
were obtained regardless of the use of background diuretic therapy or dose of diuretic therapy. …

Effect of dapagliflozin on anaemia in DAPAHF

…, DAPAHF Investigators and Committees - … of heart failure, 2021 - Wiley Online Library
… In conclusion, in patients with HFrEF in DAPA-HF, those with anaemia had worse
outcomes. Dapagliflozin corrected anaemia more often than placebo and improved outcomes, …

Effect of dapagliflozin in patients with HFrEF treated with sacubitril/valsartan: the DAPA-HF trial

SD Solomon, PS Jhund, BL Claggett, P Dewan… - Heart failure, 2020 - jacc.org
… This study assessed the efficacy and safety of dapagliflozin in patients who … in DAPA-HF,
we could not directly assess the potential incremental value of treatment with both dapagliflozin