Dapagliflozin in a real-world chronic heart failure population: how many are actually eligible?

S Maltês, GJL Cunha, BML Rocha, J Presume… - Cardiology, 2021 - karger.com
… When comparing our cohort of patients with LVEF ≤40% to the dapagliflozin arm in DAPA-HF
our cohort of chronic HFrEF patients were eligible for dapagliflozin according to the DAPA-…

Two tales: one story: EMPEROR-Reduced and DAPA-HF

S Verma, DK McGuire, MN Kosiborod - Circulation, 2020 - Am Heart Assoc
DAPA-HF (Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure; with dapagliflozin)
2,… of SGLT2 inhibitors to treat patients with heart failure with reduced ejection fraction (…

Extrapolating long-term event-free and overall survival with dapagliflozin in patients with heart failure and reduced ejection fraction: an exploratory analysis of a phase …

KF Docherty, PS Jhund, B Claggett, JP Ferreira… - JAMA …, 2021 - jamanetwork.com
… of the Dapagliflozin and Prevention of Adverse-Outcomes in Heart Failure (DAPA-HF) trial,
we … In this post hoc analysis of DAPA-HF, we used previously described methods to enable …

Use of Win Statistics to Analyze Outcomes in the DAPA-HF and DELIVER Trials

T Kondo, SB Gasparyan, PS Jhund… - NEJM …, 2023 - evidence.nejm.org
… The primary end point in most heart failure (HF) trials is a composite of time to a first … We
examined the effects of dapagliflozin compared with placebo on a hierarchical composite …

Eligibility of Dapagliflozin and Empagliflozin in a Real‐World Heart Failure Population

E Håkansson, H Norberg, S Själander… - Cardiovascular …, 2021 - Wiley Online Library
… Characteristics for the patients in our population that were eligible for DAPA-HF and
EMPEROR-reduced compared to the cohorts receiving dapagliflozin and empagliflozin in respective …

Efficacy of dapagliflozin according to geographic location of patients with heart failure

T Kondo, X Wang, M Yang, PS Jhund… - Journal of the American …, 2023 - jacc.org
… of dapagliflozin in HF were consistent across regions using individual patient data from >11,000
participants enrolled in 2 placebo-controlled randomized trials, DAPA-HF (Dapagliflozin

Dapagliflozin versus placebo on left ventricular remodeling in patients with diabetes and heart failure: the REFORM trial

JSS Singh, IR Mordi, K Vickneson, A Fathi… - Diabetes …, 2020 - Am Diabetes Assoc
… We were unable to determine with certainty whether dapagliflozin in patients with T2DM and
HF had any effect on LV remodeling. Whether the benefits of dapagliflozin in HF are due to …

Effects of Dapagliflozin on Physical and Social Activity Limitations in Patients With Heart Failure and Reduced Ejection Fraction: An Analysis of DAPA-HF

K Docherty, MN Kosiborod, SE Inzucchi, L Kober… - Circulation, 2020 - Am Heart Assoc
… We examined whether the SGLT2 inhibitor dapagliflozin improved the degree of physical …
Kansas City Cardiomyopathy Questionnaire (KCCQ) in DAPA-HF. Hypothesis: Dapagliflozin, …

The clinical outcomes of dapagliflozin in patients with acute heart failure: A randomized controlled trial (DAPA-RESPONSE-AHF)

AN Emara, M Wadie, NO Mansour… - European Journal of …, 2023 - Elsevier
… the effect of dapagliflozin on symptomatic relief in those patients. … of patients with heart
failure treated with dapagliflozin experienced clinically meaningful improvements in heart failure-…

[HTML][HTML] Eligibility for dapagliflozin and empagliflozin in a real-world heart failure population

T Thorvaldsen, G Ferrannini, L Mellbin, L Benson… - … of Cardiac Failure, 2022 - Elsevier
… In this large, contemporary, non-selective real-world HF population, we found that
eligibility for dapagliflozin and empagliflozin based on the eligibility criteria from the DAPA-HF, …