[HTML][HTML] Dapagliflozin in patients with heart failure and reduced ejection fraction

JJV McMurray, SD Solomon, SE Inzucchi… - … England Journal of …, 2019 - Mass Medical Soc
… , we randomly assigned 4744 patients with New York Heart Association class II, III, or IV
heart failure and an ejection fraction of 40% or less to receive either dapagliflozin (at a dose of …

[HTML][HTML] Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

SD Solomon, JJV McMurray, B Claggett… - … England Journal of …, 2022 - Mass Medical Soc
patients with heart failure and a left ventricular ejection fraction of more than 40% to receive
dapagliflozin (… The primary outcome was a composite of worsening heart failure (which was …

Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to age: insights from DAPA-HF

FA Martinez, M Serenelli, JC Nicolau, MC Petrie… - Circulation, 2020 - Am Heart Assoc
… of mortality and heart failure hospitalization and improved symptoms in patients with heart
failure and reduced ejection fraction. We examined the effects of dapagliflozin according to …

Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF

PS Jhund, SD Solomon, KF Docherty, HJL Heerspink… - Circulation, 2021 - Am Heart Assoc
patients with heart failure and reduced ejection fraction (HFrEF) have chronic kidney disease
… We assessed the safety and efficacy of dapagliflozin in patients with HFrEF, according to …

Time to clinical benefit of dapagliflozin and significance of prior heart failure hospitalization in patients with heart failure with reduced ejection fraction

DD Berg, PS Jhund, KF Docherty, SA Murphy… - JAMA …, 2021 - jamanetwork.com
… in risk of cardiovascular death or worsening heart failure when dapagliflozin was initiated
in patients with heart failure with reduced ejection fraction, with particularly large absolute risk …

[HTML][HTML] The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

ME Nassif, SL Windsor, BA Borlaug, DW Kitzman… - Nature medicine, 2021 - nature.com
Patients with heart failure and preserved ejection fraction (HFpEF) have a high burden of …
patients with HFpEF (NCT03030235), we evaluated whether the SGLT2 inhibitor dapagliflozin

[HTML][HTML] Dapagliflozin in heart failure with improved ejection fraction: a prespecified analysis of the DELIVER trial

O Vardeny, JC Fang, AS Desai, PS Jhund, B Claggett… - Nature Medicine, 2022 - nature.com
… and safety of dapagliflozin in patients with HFimpEF. We hypothesized that patients with
HFimpEF would benefit from dapagliflozin to a similar extent as patients with LVEF consistently …

Effects of dapagliflozin on symptoms, function, and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial

MN Kosiborod, PS Jhund, KF Docherty, M Diez… - Circulation, 2020 - Am Heart Assoc
… in patients with heart failure and reduced ejection fraction. In this analysis, we examine
the effects of dapagliflozin on a … , using the Kansas City Cardiomyopathy Questionnaire (KCCQ). …

Dapagliflozin in heart failure with preserved and mildly reduced ejection fraction: rationale and design of the DELIVER trial

SD Solomon, RA de Boer, D DeMets… - … of heart failure, 2021 - Wiley Online Library
… of DAPA-HF that data from both dapagliflozin heart failure trials, DAPA-HF and DELIVER, will
… meta-analysis to assess the effect of dapagliflozin across the full spectrum of heart failure. …

[HTML][HTML] Dapagliflozin: a review in symptomatic heart failure with reduced ejection fraction

HA Blair - American Journal of Cardiovascular Drugs, 2021 - Springer
… The cardiovascular (CV) benefits of dapagliflozin were first observed in the DECLARE-TIMI …
of dapagliflozin in patients with symptomatic heart failure with reduced ejection fraction in the …