Time to clinical benefit of dapagliflozin in patients with heart failure with mildly reduced or preserved ejection fraction: a prespecified secondary analysis of the …

M Vaduganathan, BL Claggett, P Jhund… - JAMA …, 2022 - jamanetwork.com
Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction.  … 2 inhibitor
dapagliflozin first apparent among patients with heart failure with mildly reduced or preserved …

Metabolomic profiling of the effects of dapagliflozin in heart failure with reduced ejection fraction: DEFINE-HF

S Selvaraj, Z Fu, P Jones, LC Kwee, SL Windsor… - Circulation, 2022 - Am Heart Assoc
Background: Sodium-glucose cotransporter-2 inhibitors are foundational therapy in patients
with heart failure with reduced ejection fraction (HFrEF), but underlying mechanisms of …

Effects of dapagliflozin in patients with kidney disease, with and without heart failure

JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Heart Failure, 2021 - jacc.org
… of dapagliflozin in chronic kidney disease (CKD) patients, with and without heart failure (HF). …
We did not have a measurement of left ventricular ejection fraction and do not, therefore, …

Effects of dapagliflozin according to QRS duration across the spectrum of left ventricular ejection fraction: An analysis of DAPA‐HF and DELIVER

A Abdin, T Kondo, M Böhm, PS Jhund… - … of Heart Failure, 2024 - Wiley Online Library
patients with a paced rhythm and cardiac resynchronization therapy. Overall, 4008
patients had heart failure (HF) with reduced ejection fraction (… /preserved ejection fraction (HFmrEF/…

Atrial fibrillation and dapagliflozin efficacy in patients with preserved or mildly reduced ejection fraction

JH Butt, T Kondo, PS Jhund, J Comin-Colet… - Journal of the American …, 2022 - jacc.org
dapagliflozin according to the presence or not of AF in the DELIVER (Dapagliflozin Evaluation
to Improve the LIVEs of Patientspatients with heart failure and preserved ejection fraction (…

Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction according to polypharmacy status

A Peikert, P Goyal, M Vaduganathan, BL Claggett… - Heart Failure, 2023 - jacc.org
… (Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction
Heart Failure) trial, we sought to examine the efficacy and safety of dapagliflozin according to …

Effect of dapagliflozin according to baseline systolic blood pressure in the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure trial (DAPA-HF)

M Serenelli, M Böhm, SE Inzucchi, L Køber… - European heart …, 2020 - academic.oup.com
patients with heart failure and reduced ejection fraction (HFrEF). We evaluated the efficacy
and safety of dapagliflozin… SBP in Dapagliflozin and Prevention of Adverse Outcomes in Heart

Cost‐effectiveness of dapagliflozin as a treatment for heart failure with reduced ejection fraction: a multinational health‐economic analysis of DAPA‐HF

P McEwan, O Darlington, JJV McMurray… - … of heart failure, 2020 - Wiley Online Library
… To estimate the cost-effectiveness of dapagliflozin added to standard therapy, vs. standard
therapy only, in patients with heart failure (HF) with reduced ejection fraction (HFrEF), from the …

Influence of NT-proBNP on efficacy of dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

PL Myhre, M Vaduganathan, BL Claggett, ZM Miao… - Heart Failure, 2022 - jacc.org
dapagliflozin 10 mg daily or placebo, and showed that dapagliflozin reduced the composite
of cardiovascular … This analysis explores the efficacy and safety of dapagliflozin according to …

Dapagliflozin and New York Heart Association functional class in heart failure with mildly reduced or preserved ejection fraction: the DELIVER trial

JW Ostrominski, M Vaduganathan… - … of Heart Failure, 2022 - Wiley Online Library
… , we show that dapagliflozin reduced the risk of cardiovascular death or worsening HF …
among symptomatic patients irrespective of baseline NYHA functional class. Patients with more …