[HTML][HTML] Dapagliflozin in patients with heart failure and reduced ejection fraction

JJV McMurray, SD Solomon, SE Inzucchi… - … England Journal of …, 2019 - Mass Medical Soc
… group and in 502 of 2371 patients (21.2%) in the placebo group (hazard ratio, 0.74; 95… heart
failure event occurred in 237 patients (10.0%) in the dapagliflozin group and in 326 patients (…

Effects of dapagliflozin in patients with kidney disease, with and without heart failure

JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Heart Failure, 2021 - jacc.org
… Definite or probable ketoacidosis occurred in 2 patients without heart failure randomly
allocated to placebo; there were no cases of ketoacidosis in the dapagliflozin group. …

Dapagliflozin in Patients with Chronic Heart Failure: A Systematic Review and Meta‐Analysis

R Cai, Y Xu, Q Su - Cardiology research and practice, 2021 - Wiley Online Library
… safety of dapagliflozin for the management of chronic heart failure. We showed that dapagliflozin
can … death/hospitalization for heart failure, cardiovascular death, and hospitalization for …

Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes

MC Petrie, S Verma, KF Docherty, SE Inzucchi, I Anand… - Jama, 2020 - jamanetwork.com
Dapagliflozin in patients with heart failure and reduced … Failure (DAPA-HF) trial included
patients with heart failure and … Dapagliflozin reduced the risk of worsening heart failure events …

Time to clinical benefit of dapagliflozin and significance of prior heart failure hospitalization in patients with heart failure with reduced ejection fraction

DD Berg, PS Jhund, KF Docherty, SA Murphy… - JAMA …, 2021 - jamanetwork.com
… or worsening heart failure when dapagliflozin was initiated in patients with heart failure with
… large absolute risk reductions in patients with a more recent heart failure hospitalization. …

[HTML][HTML] Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

SD Solomon, JJV McMurray, B Claggett… - … England Journal of …, 2022 - Mass Medical Soc
patients with heart failure and a left ventricular ejection fraction of more than 40% to receive
dapagliflozin (… The primary outcome was a composite of worsening heart failure (which was …

Effect of dapagliflozin on heart failure and mortality in type 2 diabetes mellitus

ET Kato, MG Silverman, O Mosenzon, TA Zelniker… - Circulation, 2019 - Am Heart Assoc
… transporter 2 inhibition with dapagliflozin, in addition to … heart failure to a greater extent
in patients with heart failure with reduced ejection fraction than in those without heart failure

Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF

PS Jhund, SD Solomon, KF Docherty, HJL Heerspink… - Circulation, 2021 - Am Heart Assoc
Failure), the SGLT2 inhibitor dapagliflozin reduced the incidence of the primary composite
outcome of cardiovascular death or worsening heart failure (HF) in patients … of dapagliflozin

Effects of dapagliflozin in DAPA-HF according to background heart failure therapy

KF Docherty, PS Jhund, SE Inzucchi… - European heart …, 2020 - academic.oup.com
… In the DAPA-HF trial, the SGLT2 inhibitor dapagliflozin reduced the risk of worsening
heart failure (HF) and death in patients with HF and reduced ejection fraction. We examined …

Dapagliflozin effects on biomarkers, symptoms, and functional status in patients with heart failure with reduced ejection fraction: the DEFINE-HF trial

ME Nassif, SL Windsor, F Tang, Y Khariton, M Husain… - Circulation, 2019 - Am Heart Assoc
… In patients with heart failure and reduced ejection fraction, use of … These beneficial effects
of dapagliflozin in heart failure with reduced ejection fraction may potentially extend to patients