[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been … Cytokine storms (CSs) are associated
with various pathologies, as … these cytokine-mediated inflammatory PCD pathways as ‘…

[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… -dependent enhancement, and especially, cytokine storm (CS)… cytokines initiate different
inflammatory signaling pathways via … fever, capillary leak syndrome, disseminated intravascular …

Highways to hell: Mechanism-based management of cytokine storm syndromes

SW Canna, RQ Cron - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
… Since the first textbook devoted to cytokine storm syndromes (CSSs) was published in 2019,
… Likewise, the utility of a broad term such as “cytokine storm” is that it reflects a convergence …

Plcγ2/Tmem178 dependent pathway in myeloid cells modulates the pathogenesis of cytokine storm syndrome

S Mahajan, CE Decker, Z Yang, D Veis, ED Mellins… - Journal of …, 2019 - Elsevier
… is known to be dependent on CD8 + T … cytokine storm cannot be perpetrated in the absence
of monocytes/macrophages at disease onset. In a second CSS mouse model dependent on …

The multifaceted immunology of cytokine storm syndrome

PY Lee, RQ Cron - The Journal of Immunology, 2023 - journals.aai.org
pathways to cytokine storm syndrome. (A) A cytolytic lymphocyte (top) lyses an APC (target
cell below) via the perforin pathway by … the inflammatory response was dependent on cellular …

[HTML][HTML] Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
… to be the “cytokine storm” [also called “cytokine storm syndrome” (… (ICD) does not include
the cytokine storm or CSS. Cron and … Through MyD88-dependent or TRIF-dependent pathway, …

The cytokine storm of COVID-19: a spotlight on prevention and protection

L Pearce, SM Davidson, DM Yellon - Expert Opinion on …, 2020 - Taylor & Francis
… oxide (NO) dependent increase in vascular permeability, … this pathway would disrupt the
signaling of multiple cytokines … as a result of cardio-renal syndrome, cytokine release and global …

[HTML][HTML] Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
… release syndrome (CRS) or hyper-cytokine syndrome [1], is … However, the concept of cytokine
storm is not limited to … )-dependent and MyD88-independent signaling pathways will be …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
… from a condition called “cytokine storm” or “cytokine release syndrome” could have a disastrous
… Also, a recent study reported NF-κB-dependent production of inflammatory cytokines

Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19

M Manik, RK Singh - Journal of medical virology, 2022 - Wiley Online Library
… TLR7 and activate the MyD88-dependent MAPK - NF-κB pathway leading to the
production of TNF-α, ILs, especially … -driven immune dysregulation or macrophage-activation-syndrome. …