… We will also present and discuss data on the variable extent to which information on the
impact of transporters on drug disposition is included in summaries of product characteristics of …

… developers to study which pathways are responsible for the disposition of a drug. In this … of
drug disposition, we summarize current knowledge on pharmacogenetics and drug disposition…

… in drug pharmacokinetics. Transporters are among the key determinants of drug disposition.
… , I will also discuss the prospects for future studies on transportermediated drug disposition. …

… circulation on drug disposition were investigated in 53 cirrhotic patients with portal
hypertension using indocyanine green (ICG) and lidocaine as model drugs. ICG disposition was …

… determinants of drug disposition and effects. In our opinion, genotyping results will be of
greatest clinical value if they are reported and interpreted according to the patient's diagnosis …

… Drug transporters are well-recognized determinants of drug … This book will focus on the
roles of drug transporters in drug disposition and effects/toxicity. It will also cover drug-drug …

… on drug dispoSition, the con· cepts developed can apply to analysis of the other basic
biological determinants of drug … by variations in the biological determinants of drug dispoSition. …

… are major determinants of drug bioavailability for these poorly permeable drugs and both …
provide predictability in characterizing drug disposition profiles for all classes of compounds. …

… the following subject areas: The determinants of placental transfer with emphasis on how …
influences fetal drug disposition. The fetal hepatic circulation and its effect on drug metabolism. …

… determinants of the acute and subjective effects of a drug. Rapid and complete absorption
are associated with a rapid onset of the effects of that drug (Breimer & de Boer 1975); drugs …