Heterogeneity and homogeneity of regional brain structure in schizophrenia: a meta-analysis

SP Brugger, OD Howes - JAMA psychiatry, 2017 - jamanetwork.com
schizophrenia as a heterogeneous disorder by showing, for the first time to our knowledge,
altered structural variability across a number of brain regions… structural heterogeneity may be …

[PDF][PDF] Regional heterogeneity in gene expression, regulation, and coherence in the frontal cortex and hippocampus across development and schizophrenia

L Collado-Torres, EE Burke, A Peterson, JH Shin… - Neuron, 2019 - cell.com
… hippocampal functional coherence in schizophrenia. These results underscore the complexity
and regional heterogeneity of the transcriptional correlates of schizophrenia and offer new …

Brain heterogeneity in schizophrenia and its association with polygenic risk

…, Karolinska Schizophrenia Project Consortium - JAMA …, 2019 - jamanetwork.com
heterogeneous in the schizophrenia group compared with healthy controls. B, Polygenic risk
for schizophrenia was not associated with mean changes or dispersion in any of the regions

Mapping the heterogeneous phenotype of schizophrenia and bipolar disorder using normative models

T Wolfers, NT Doan, T Kaufmann, D Alnæs… - JAMA …, 2018 - jamanetwork.com
… structural heterogeneity in adults with schizophrenia and bipolar disorder by mapping regional
… estimates of the heterogeneity among patients with schizophrenia and bipolar disorder by …

[HTML][HTML] Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia

MA Di Biase, MP Geaghan, WR Reay, J Seidlitz… - Molecular …, 2022 - nature.com
… Here, we show that CTh heterogeneity in schizophrenia relates to cellular processes
deduced from whole-brain transcriptomic and person-specific genomic data. Across two …

Domains of psychopathology: an approach to the reduction of heterogeneity in schizophrenia

RW Buchanan, WT Carpenter - The Journal of nervous and mental …, 1994 - journals.lww.com
… The manifest clinical heterogeneity of schizophrenia, combined with the … of Schizophrenia
as a pathophysiologically heterogeneous disorder. Various approaches have been developed

Cortical surface complexity in frontal and temporal areas varies across subgroups of schizophrenia

I Nenadic, RA Yotter, H Sauer… - Human brain mapping, 2014 - Wiley Online Library
region, and increase in the left posterior cingulate cortex. Our findings suggest regional
heterogeneity … related to biological subgroups of schizophrenia with differing degrees of altered …

Cognitive heterogeneity in schizophrenia

EM Joyce, JP Roiser - Current opinion in psychiatry, 2007 - journals.lww.com
… This review summarizes recent neuropsychological studies of schizophrenia, aimed at … of
neuropsychological measures in patients with schizophrenia, and studies that have attempted …

Attacking heterogeneity in schizophrenia by deriving clinical subgroups from widely available symptom data

D Dickinson, DN Pratt, EJ Giangrande… - Schizophrenia …, 2018 - academic.oup.com
… the schizophrenia spectrum disorders may help to integrate clinical and neuroscience
approaches to heterogeneity … with schizophrenia have “a separate disease within the syndrome of …

[PDF][PDF] Clusters of psychosis: compensation as a contributor to the heterogeneity of schizophrenia

L Palaniyappan - Journal of Psychiatry & Neuroscience: JPN, 2023 - jpn.ca
… patients with schizophrenia, 46% had supranormal deviations of at least 1 brain region.… to
explain the full spectrum of anatomic heterogeneity in schizophrenia. An interesting feature of …