Cytokine signaling-regulation of the immune response in normal and critically ill states

A Oberholzer, C Oberholzer, LL Moldawer - Critical care medicine, 2000 - journals.lww.com
response of critically ill patients to their injury and/or invading pathogens is dependent, in
large part, on the pattern of cytokines … may be another cytokine or even the same cytokine that …

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
responses caused by these viruses. Our curation indicates that the cytokine response
induced by SARS-CoV-2 is different … cause atypical cytokine responses in severely ill patients, …

The cytokine response to critical illness.

BA Foex, MP Shelly - Emergency Medicine Journal, 1996 - emj.bmj.com
… Conclusions The original premise in this review was that knowledge about cytokines is
important on a number of different levels in the seriously ill patient. Has this been borne out? …

Longitudinal cytokine profile in patients with mild to critical COVID-19

L Ling, Z Chen, G Lui, CK Wong, WT Wong… - Frontiers in …, 2021 - frontiersin.org
… groups with different disease severity. The secondary objective was to … cytokines and clinical
endpoints in critically ill patients. A total of 40 adult patients (mild = 8, moderate = 15, severe/…

[HTML][HTML] Immune response in critically ill patients

M Surbatovic, D Vojvodic, W Khan - Mediators of Inflammation, 2018 - ncbi.nlm.nih.gov
… -1, sCD14, IL-6, and IL-10 were significantly higher in patients with … Patients were divided
into four subgroups: peritonitis, pancreatitis, … There was no significant difference of investigated …

Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis

FA Bozza, JI Salluh, AM Japiassu, M Soares, EF Assis… - Critical care, 2007 - Springer
… high-risk patients with sepsis is a great challenge in the care of critically ill patients [1, 2]. …
to other groups of patients. Furthermore, only one time point was used for the measurement of …

[HTML][HTML] Plasma cytokine levels predict mortality in patients with acute renal failure

EM Simmons, J Himmelfarb, MT Sezer, GM Chertow… - Kidney international, 2004 - Elsevier
… of literature reporting plasma cytokines in critically ill patients, especially patients with sepsis.
In … Another notable finding in this study is the inverse association of baseline circulating …

Clinical associations of host genetic variations in the genes of cytokines in critically ill patients

OB Belopolskaya, TV Smelaya… - Clinical & …, 2015 - academic.oup.com
… These findings suggest that genetic variability in pro- and anti-inflammatory cytokines
may contribute to different clinical phenotypes in patients at high risk of critical illness. …

Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes

DE Leisman, L Ronner, R Pinotti, MD Taylor… - The Lancet …, 2020 - thelancet.com
Other cytokine measures in the subgroup of patients with critical COVID-19 were similar to
… -cytokine biomarkers appeared to be exaggerated in the group with critical versus severe

Serial cytokine levels in patients with severe sepsis

HP Wu, CK Chen, K Chung, JC Tseng, CC Hua… - Inflammation …, 2009 - Springer
… Plasma time-course curve of IL-6 was different between patients with shock and without …
reporting that IL-6 and IL-10 levels in patients with severe sepsis were different between survivor …