P Xu, H He, Q Gao, Y Zhou, Z Wu… - The Journal of …, 2022 - Am Soc Clin Investig
… mDA neuron differentiation in vitro and graft composition in vivo, we revealed the developmental basis of both target and off-target neuronal cells that emerge during differentiation and …
NL Estrella, CA Desjardins, SE Nocco, AL Clark… - Journal of biological …, 2015 - ASBMB
… programs. These results suggest that individual MEF2 family members are able to recognize specific targets … their respective gene programs in skeletal muscle homeostasis and disease.…
E Six, A Guilloux, A Denis, A Lecoules… - Blood, The Journal …, 2020 - ashpublications.org
… Our results suggested that in at least 2 distinct genetic diseases, human hematopoiesis after gene therapy is maintained by several distinct HSPC subsets, rather than a single subset of …
… , mediators and differentiationprograms that are responsible for SSc … diseases and asthma. Thus the PPAR-γ pathway represents an appealing therapeutic target in a variety of diseases…
D Amsen, C Helbig, RA Backer - Trends in immunology, 2015 - cell.com
… such diverse differentiationprograms. Studies … target Notch in T cells for therapeutic purposes. There are efforts to mitigate detrimental responses, such as in allergic asthma, a disease …
… gene expression in NSC by affecting intrinsic transcriptional programs (red arrows). Sonic … , to target endogenous NSC. Indeed, strategies aiming at in situ differentiation of endogenous …
J Lin, J Tian, X Fang, B Zhang, Y Yang… - Advanced Chinese …, 2024 - Wiley Online Library
… diseasetarget (target formula/herb with specific curative effects on diseases), symptom target (target … on clinical symptoms), and indicator target (target formula/herb with special impact …
… ES cell differentiation-specific gene expression programs [101… at the target DNA upon induction of neuronal differentiation, … for activation during ES cell differentiation and that stem cell …
A Melnick, JD Licht - Blood, The Journal of the American …, 1999 - ashpublications.org
… complete remissions by differentiation and eventual elimination of … , leading to in vivo differentiation and clinical remission. … Finally, we will reconstruct the disease of APL and examine …