… In early January 2020, a virus was sequenced and identified as a novel coronavirus named SARS-CoV-2, the causative agent of COVID-19. By March 2020, the World Health …
… against SARS‐CoV‐2 … SARS‐CoV‐2 indicative of diseasetolerance. Insights from this study highlight key immune pathways that could serve as therapeutic targets to prevent disease …
NJ Silverstein, Y Wang, Z Manickas-Hill, C Carbone… - medRxiv, 2021 - ncbi.nlm.nih.gov
… amphiregulin, a protein implicated in diseasetolerance and tissue homeostasis, and … diseasetolerance, homeostatic ILCs decrease morbidity and mortality associated with SARS-CoV-…
T Flerlage, DF Boyd, V Meliopoulos… - Nature Reviews …, 2021 - nature.com
… Diseasetolerance refers to a host response that acts to limit … In the respiratory tract, a strategy of tolerance would maintain … The concepts of resistance and tolerance are often employed …
N Todorović-Raković, JR Whitfield - Cytokine, 2021 - Elsevier
… Tolerance refers to the capacity of a host to limit the damage caused by both, immune-… of tolerance as a peculiar form of evolutionary adaptation. Enhanced infection tolerance may be …
MJ Castleman, MM Stumpf, NR Therrien… - Journal of Experimental …, 2022 - rupress.org
… stimuli can breach peripheral B cell tolerance in this subset. We asked whether SARS-CoV-2–associated inflammation impairs B ND cell peripheral tolerance. To address this, PBMCs …
… the differences in COVID-19 diseases severity in the young versus the … disease manifestations and their possible disease … of SARS-CoV-2 infections in children and young people. …
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) … can contribute to autoimmune disease, which has been … -reg by the SARS-CoV-2 reduces self-tolerance and leads to …
R Naveen, E Nikiphorou, M Joshi, P Sen… - …, 2023 - academic.oup.com
… Active and inactive disease state four weeks prior to … was the status of your autoimmune disease in the four weeks (prior to) … disease were grouped together to designate ‘active disease’. …