Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm

PA Mudd, JC Crawford, JS Turner, A Souquette… - Science …, 2020 - science.org
unique ways in which COVID-19 modulates cytokine profiles, we focused the majority of
cytokine … dominant response profile among patients with COVID-19 consisted of more selective …

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
… a map of patient-derived cytokine responses given to different CRS-causing viruses. Our
goal is that such a resource of unique and conserved cytokine responses will aid specialists to …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… in cytokine levels while discussing cytokine sources and biological functions. Finally, we
discuss in brief potential therapies attempting to modulate the cytokine storm. … and the distinct

The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
… A cytokine storm (CS) is a clinically relevant condition that has been associated with several
… (DAMPs) with pattern recognition receptors evoke similar cytokine profiles in mammals. …

Distinct patterns of blood cytokines beyond a cytokine storm predict mortality in COVID-19

C Herr, S Mang, B Mozafari, K Guenther… - … of Inflammation …, 2021 - Taylor & Francis
… In conclusion, COVID-19 shows a distinct inflammatory blood marker profile separate from
conventional pneumonia and extrapulmonary disease. Several markers were associated with …

Cytokine storm signature in patients with moderate and severe COVID-19

O Kalinina, A Golovkin, E Zaikova, A Aquino… - International Journal of …, 2022 - mdpi.com
… The patients from both groups and healthy donors form tighter but separate clusters
based on their cytokine profiles, whereas patient’s groups clusters partially overlap (Figure 2B). …

Comparing the cytokine storms of COVID-19 and pandemic influenza

LM Pacheco-Hernández… - … interferon & cytokine …, 2022 - liebertpub.com
… This review compares cytokine storm syndromes (CSS) observed … unique immune profiles
in critical COVID-19, we provide the theoretical bases for future research on specific cytokine

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
different chemokine profiles between the two groups. Moreover, the circulating levels of
CCL2 were nearly doubled (264 vs. 134 pg/mL) in the severe group compared to non-severe …

[HTML][HTML] Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19

JT Sims, V Krishnan, CY Chang, SM Engle… - Journal of Allergy and …, 2021 - Elsevier
… 2 dimensions, we observed 2 distinct sample groups segregating on the basis of severity
of disease (data not shown). This indicates that inflammatory proteins observed in the plasma …

The advent of the cytokine storm

IA Clark - Immunology and cell biology, 2007 - search.proquest.com
… The term ‘cytokine storm’ is now used in popular culture as an explanation for the distinctly
… ) can be expected to generate different ranges, profiles, concentrations and kinetics of …