Distinct patterns of blood cytokines beyond a cytokine storm predict mortality in COVID-19

C Herr, S Mang, B Mozafari, K Guenther… - Journal of …, 2021 - Taylor & Francis
… Therefore, we propose the use of a pattern of distinct cytokine markers, that can be easily
determined by standard laboratory methods to predict the course of COVID-19. Elevated …

The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been … Cytokine storms (CSs) are associated
with various pathologies, as … cytokine release and cell death pathways; certain cytokines, …

Comparing the cytokine storms of COVID-19 and pandemic influenza

LM Pacheco-Hernández… - … interferon & cytokine …, 2022 - liebertpub.com
… This review compares cytokine storm syndromes (CSS) observed during COVID-19 and …
cytokine networks implicated in pathogenesis that could be targeted through immunotherapy. …

Cytokine storm signature in patients with moderate and severe COVID-19

O Kalinina, A Golovkin, E Zaikova, A Aquino… - International Journal of …, 2022 - mdpi.com
cytokine storm signatures in patients with acute COVID-19 and to investigate their influence
on severity of the infection. Plasma levels of 47 cytokines were … Careful definition of distinct

Clinical features of cytokine storm syndrome

M Shimizu - Cytokine storm syndrome, 2019 - Springer
Cytokine storm syndrome (CSS ) is a severe life-threating … cytokines, causing a cytokine
storm. Many clinical features of CSS can be explained by the effects of proinflammatory cytokines

Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm

PA Mudd, JC Crawford, JS Turner, A Souquette… - Science …, 2020 - science.org
cytokine profiles indicative of cytokine storm syndrome. After controlling for multiple factors
including age and sample time point, patients with COVID-19 exhibited lower cytokine levels …

Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
The human innate and adaptive immune systems consist of effector cells producing cytokines
(interleukins, interferons, chemokines, and numerous other mediators). Usually, a fragile …

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
cytokine/chemokine network is crucial in the onset and maintenance of the “cytokine storm”,
… a specific focus on their role in the cytokine storm and ultimately with their ability to predict …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… in cytokine levels while discussing cytokine sources and biological functions. Finally, we
discuss in brief potential therapies attempting to modulate the cytokine storm. … and the distinct

Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
… mechanisms underlying cytokine storm induction and … cytokine storms are described from
both host and pathogen perspectives. In summary, current studies indicate that cytokine storm-…