S Yair, G Coop - … Transactions of the Royal Society B, 2022 - royalsocietypublishing.org
… In our models, we focus on divergence without gene flow between a pair of populations, in which case they only share polymorphisms that arose in their common ancestor and were not …
KA Bird - American journal of physical anthropology, 2021 - Wiley Online Library
… This analysis employs the current most reliable methods given concerns over cross-population polygenicscore analysis. It demonstrates that patterns of genetic differences between …
… or with different magnitudes in the same direction, and therefore need not increase genetic differences between populations in the way that divergent selection for the initial trait might …
… -population variation and correlation with latitude to identify signals of polygenic adaptation on two highly polygenic … The correlation of polygenicscores with average population trait (…
TB Cavazos, JS Witte - Human Genetics and Genomics Advances, 2021 - cell.com
… ancestry populations. Our simulations show that the magnitude of this bias increases with increasing divergence from European ancestry, and this is attributed to population differences …
R Avinun, A Nevo, SR Radtke, BD Brigidi… - European archives of …, 2020 - Springer
… As higher DA polygenicscores putatively index higher in vivo DA … DA polygenicscores and lower depressive symptoms in the Duke Neurogenetics Study (DNS). To avoid population …
… The lowest prediction accuracy is in populations with southern African ancestry, consistent also with higher genetic divergence from European populations and more genetic diversity …
… divergence from the makeup of the discovery GWAS; therefore, the accuracy … polygenic scores in different populations is highly dependent on the representation of the study population …
… population genetic theory and avoid or remedy many of the known biases of polygenic scores. … We can define the divergence of the means of populations (μi ) from the grand …