L Premkumar, B Segovia-Chumbez, R Jadi… - Science …, 2020 - science.org
… with SARS-CoV-1 or SARS-CoV-2 spikeproteins to assess … SARS-CoV-2 spikeprotein had antibodies that bound well to the RBD of SARS-CoV-2 and poorly to the RBDs of SARS-CoV-…
L Du, G Zhao, Y He, Y Guo, BJ Zheng, S Jiang, Y Zhou - Vaccine, 2007 - Elsevier
… (SARS) coronavirus (SARS-CoV) is still a priority in prevention of re-emergence of SARS. … that the receptor-binding domain (RBD) of SARS-CoVspike (S) protein elicits highly potent …
Y He, Y Zhou, S Liu, Z Kou, W Li, M Farzan… - … and biophysical research …, 2004 - Elsevier
… fusion protein containing the RBD of SARS-CoV S protein (residues … S1 protein to ACE2 and potently neutralize SARS-CoV and SARS pseudovirus, suggesting that the RBD of S protein …
… S on mature SARS-CoV virions does not appear to be cleaved, and the sequence that … The SARS-CoVspikeprotein RBD. (A) Domain structure of the SARS-CoVspikeprotein. The …
WH Chen, L Du, SM Chag, C Ma… - Human vaccines & …, 2014 - Taylor & Francis
… SARS vaccine antigen consisting of the receptor-binding domain (RBD) of SARS-CoVspike protein … responses and protection against SARS-CoV challenge in vaccinated animals. To …
S Wang, F Guo, K Liu, H Wang, S Rao, P Yang, C Jiang - Virus research, 2008 - Elsevier
… -Fc protein could bind to ACE2. We demonstrated that the RBD spikeprotein alone could be internalized into SARS-CoV … of N-glycans from the RBD spikeprotein did not abolish this …
L Du, Y He, Y Zhou, S Liu, BJ Zheng… - Nature Reviews …, 2009 - nature.com
… Because the SARS-CoV S protein S2 domain also contains HR1 and HR2 sequences, we … of the SARS-CoV S protein S2 domain would also have antiviral activity against SARS-CoV. …
Z Cao, L Liu, L Du, C Zhang, S Jiang, T Li, Y He - Virology journal, 2010 - Springer
Background The spike (S) protein of SARS-CoV not only mediates receptor-binding but also induces neutralizing antibodies. We previously identified the receptor-binding domain (RBD…
J Zhang, T Xiao, Y Cai, B Chen - Current opinion in virology, 2021 - Elsevier
… This paper shows that the receptor-binding domains of SARS-CoV-2 S and SARS-CoV S bind with similar affinities to human ACE2, and that the furin cleavage site at the boundary …