… TMDs have now been implicated in virus assembly, protein sorting, oligomerization and
fusion. Here, we report the importance of the TMD of the SARS CoV spike protein for mediating …

… coronavirus, which was named SARS coronavirus (SARS-… of cleavage of the SARS-CoV
spike protein occurs. Recently, … showing that SARS S is cleaved during entry of the virus rather …

… The clue behind the SARS-CoV-2 origin is still a matter of debate. Here, we report that
SARS-CoV-2 has gained a novel spike protein S1–N-terminal domain (S1-NTD). In our CLuster …

… Here, we identify a proteolytic cleavage site within the SARS-CoV S2 domain (S2′, R797).
Mutation of R797 specifically inhibited trypsin-dependent fusion in both cell–cell fusion and …

… For the binding domain, we used the crystal structure of SARS-CoV-2 RBD that is bound to
… spike protein body of SARS-CoV2 compared to the fatter spike protein body of SARS-CoV. It …

… The variation analyses in amino acids indicated the structural features of different domains
of the SARS-CoV-2 spike proteins. The variations have multiple effects on the structure …

… , the spike protein of SARS-CoV-2 plays a critical and fundamental role in viral infection and
in comparison with SARS-CoV … domain and motif (RBM) of the S1 region of the spike protein. …

… The FP in the N-terminus of SARS-CoV-2 and the two HR domains on S2 is essential for …
The coronavirus spike protein is a class I virus fusion protein: structural and functional …

… For example, although four out of five residues critical for receptor binding are replaced in
the RBD domain of SARS-CoV-2 S glycoprotein, the SARS-CoV-2 RBD retains strong binding …

… proteins of SARS-CoV and SARS-CoV-2 to the ACE2. Our results show that the protein
surface of the ACE2 at the receptor binding domain (… for the S proteins of SARS-CoV/SARS-CoV-2…